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Biomedical subjects

N Kayser

Publications and source records attributed to N Kayser.

3 recordsLinked to original sources

[Modular memory training for elderly adults: concept and evaluation].

We present a modular concept of a cognitive training relevant to the demands of everyday life of community dwelling older adults. The concept has three major advantages. First, it takes into account the current performance levels and needs of the trainees. Second, the training is economical in aiming at selecting the most effective training elements. Third, the concept allows the evaluation of single elements of the training. The application of this concept points at the importance of training content being relevant to trainees' everyday lives. Results indicate that training effectiveness depends on the starting level of performance and the cognitive domain being trained. Overall, the results demonstrate the possibility to maximize training gains of older adults by designing adequate trainings for well-defined subgroups of normal older adults.

Activities of Daily Living↗

Clozapine for tardive dyskinesia in adolescents.

Thousands of adolescents use neuroleptic drugs over extended periods of time for a wide range of mental disorders. One of the most severe adverse effects of neuroleptic drugs is tardive dyskinesia (TD), for which no successful treatment is currently available. Clozapine is a known atypical neuroleptic drug with few extrapyramidal side effects. It has been suggested that clozapine may be beneficial for the treatment of tardive dyskinesia in adolescents. However, the efficacy of the drug in adolescents is unknown. This report describes the beneficial effect of clozapine on tardive dyskinesia in two adolescents with schizophrenia.

Adolescent↗

[Confusion and delusions occurring during interferon-alpha treatment].

A number of side effects occurring during IFN therapy have been described. Psychiatric side effects include cognitive, behavioural and affective changes, confusion and, less commonly, psychotic symptoms. We report the case of a 52-year-old patient who had been treated for almost three years with IFN alpha for a chronic myelogenous leukemia and who presented an acute confusional episode with delusions, following the reintroduction of IFN alpha after a therapy suspension of 2 weeks. Clinical improvement occurred quite rapidly after cessation of the IFN treatment; this evolution and the normality of the biological tests, EEG and cerebral imagery suggest a causal relationship between this treatment and the psychiatric symptoms.

Confusion↗