Biomedical subjects

N Kepner

Publications and source records attributed to N Kepner.

3 recordsLinked to original sources

PubMed1982

Enhanced tumor growth in vivo by a factor in human platelets and rat liver.

Liver cell supernatant and platelet extract can promote the in vivo growth of herpes simplex virus type 2-transformed hamster embryo fibroblast cells. Delineation of necessary growth factors for tumor cells in vivo may open up new strategies to inhibit malignant cell growth.

Animals↗

PubMed1982

A mitogenic factor for transformed cells from human platelets.

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Animals↗

PubMed1981

A mitogenic factor for transformed fibroblasts from human platelets.

Human platelets contain discrete glycoproteins that promote the growth of 3T3 (platelet-derived growth factor 1) and SV3T3 (platelet-derived growth factor 2) cells. The factor that promotes the growth of SV3T3 cells is a heat-labile nondialyzable glycoprotein with an isoelectric point of 7.8 to 8.3.

Animals↗