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Biomedical subjects

N Khouri

Publications and source records attributed to N Khouri.

23 records · Page 2Linked to original sources
PubMedDate not supplied

Fractures of the proximal tibial metaphysis in children: review of a series of 25 cases.

Twenty-five cases of fractures of the proximal tibial metaphysis in children are reported. They are divided into three groups: torus fractures, greenstick fractures, and complete fractures. Genu valgum appeared in 12 cases of complete or greenstick fractures. Eleven deformities deteriorated progressively in the year following trauma. Three of these were spontaneously compensated for by growth at the inferior epiphyseal plate. Four corrective osteotomies were performed in the series, but this procedure is not recommended because of the significant risk of recurrence and the possibility of compartment syndrome, even with associated fibular osteotomy. A persistent valgus deformity can be corrected during puberty, if necessary, by a medial tibial epiphysiodesis.

Casts, Surgical↗
PubMedDate not supplied

Intensive induction chemotherapy in 54 patients with small cell carcinoma of the lung.

Fifty-four patients with localized and extensive small cell carcinoma of the lung and no prior therapy were treated with intensive induction chemotherapy. The induction regimen consisted of two courses of high-dose cyclophosphamide, doxorubicin, and VP-16-213. The objective response rate was 78% (42 responses among 54 patients), with 14 complete (26%) and 28 partial (52%) responses. The median survival time for the entire group of patients is 378 days, with a projected 2-year survival rate of 22%. The most significant determinant of survival was the attainment of a complete response. Tumor progression in most relapsing patients occurred at the sites of initial involvement. Toxicity was significant, as expected, but treatment-related mortality did not exceed that of less intense regimens. Despite the use of such intensive induction regimens, the major challenge in the therapy for small cell carcinoma remains the achievement of more durable complete remissions.

Adult↗
PubMedDate not supplied

[Birth palsy of the brachial plexus--surgical exploration and attempted repair in twenty one cases (author's transl)].

Twenty one cases of birth palsy of the brachial plexus have been explored surgically. The patients were aged from seven weeks to nine years. The results of pre-operative examination are described and myelography is considered to be especially important. It was found that ruptures of the upper roots at the junction of C5-C6 were frequent and could be repaired by nerve graft. Avulsion from the spinal cord was more frequent in the lower roots. It is concluded that surgical exploration and attempted repair should be done early, preferably at the age of two or three months in cases of absence of spontaneous recovery.

Brachial Plexus↗