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Biomedical subjects

N Kilpatrick

Publications and source records attributed to N Kilpatrick.

11 recordsLinked to original sources

The self-concept of adolescents with cleft lip and palate: a pilot study using a multidimensional/hierarchical measurement instrument.

OBJECTIVE: To pilot the use of a multidimensional/hierarchical measurement instrument called the self-description questionnaire II to determine whether specific areas of self-concept in a group of adolescents with cleft lip and palate would be affected by their condition when compared with a normative sample. PARTICIPANTS AND DESIGN: The self-concept of 23 adolescents with a cleft of the lip and palate was compared to an Australian normative sample. Adolescents attending the dental department of a paediatric hospital in Australia. MAIN OUTCOME MEASURE: The main outcome measure was a self-report questionnaire (102 items) with 10 domain-specific scales and a global measure of general self-concept. RESULTS: When compared to the normative data the study group showed significant differences in 4 of the 11 domain-specific scales: Parent Relations (P < 0.001), Physical Abilities (P < 0.001), Opposite-Sex Relations (P < 0.01) and Physical Appearance (P < 0.01) self-concepts. These differences were in a positive direction. Global self-concept as measured by the General Self scale was not significantly different from the normative sample. CONCLUSION: These results suggest that adolescents with clefts of the lip and palate have normative if not better self-concept than their peers. The study also suggests that having a cleft of the lip and palate has specific rather than broad associations with psychosocial adjustment. This justifies the use of instruments designed to assess specific areas of self-concept rather than more global measures.

Adolescent↗

Canine eruption into grafted alveolar clefts: a retrospective study.

BACKGROUND: The contemporary treatment of cleft lip and palate involves a sequence of surgical procedures and orthodontic management. Alveolar bone grafting (ABG) is usually undertaken after orthodontic expansion of the maxillary segments between the ages of eight and 12 years. Two of the important goals of alveolar bone grafting are the provision of bony support for the eruption of the canine and the closure of residual oro-nasal fistulae. The purpose of this study was to retrospectively evaluate the root development and eruption of the canine following ABG. METHODS: Group 1: radiographic and clinical records of a sample of 19 cleft patients who underwent alveolar bone grafting procedures, performed between 1996 and 1999 were reviewed. Group 2: a random sample of 15 cleft patients attending for routine dental review were clinically examined. The age of patient, degree of root development and eruption status of the canine, and presence of oronasal fistulae pre and post alveolar bone grafting were evaluated. RESULTS: Most cleft canines had continued root development and descended in the alveolus towards eruption following ABG. Four canine teeth (8 per cent) were impacted and required surgical exposure and orthodontic treatment following failure of eruption. Closure of anterior oro-nasal fistulae at the time of grafting was maintained post-operatively. CONCLUSIONS: This study demonstrated that canine root development and eruption continued satisfactorily through grafted alveolar clefts in most cases and closure of anterior oro-nasal fistulae was achieved in all cases.

Adolescent↗

Molecular analysis for genetic counselling in amelogenesis imperfecta.

OBJECTIVE: To use molecular genetics to establish the mode of inheritance in a family with amelogenesis imperfecta. MATERIALS AND METHODS: The polymerase chain reaction was used to amplify exons of the amelogenin gene on the short arm of the X chromosome. RESULTS: A single base deletion mutation in exon 6 of the amelogenin gene was identified. This mutation was a single base deletion of a cytosine residue - 431delC - in codon 96 of exon 6, introducing a stop codon 30 codons downstream of the mutation in codon 126 of the exon. CONCLUSION: The firm establishment of an X-linked mode of inheritance affects the genetic counselling for this family.

Amelogenesis Imperfecta↗

Characterisation of tribochemically assisted bonding of composite resin to porcelain and metal.

OBJECTIVE: The fracture of bonded ceramic to metal restorations remains a problem in clinical dental practice. The use of resin based composites to repair such fractures is generally unsatisfactory. Tribochemical technology creates a surface layer of small silica particles fused to the surface substrate. Such a layer potentially improves adhesion of resin to both alloy and porcelain. Adhesion between two substrates is traditionally studied using shear or tensile bond strength tests. However, the highest stress at bond failure may not represent the real bonding characteristics correctly. An alternative method is to describe the bonding characteristics by determining the strain energy release rate for a given interface. This study compares the bonding characteristics of a resin to gold/porcelain interface using a tribochemical coating process with those of a control group using simple gritblasting. METHODS: Pre-cracked specimens were subjected to load-unload cycles using a simple four point bending test and the resultant strain energy release rates were calculated. RESULTS: Tribochemically pretreating the porcelain resulted in a significant increase in the resultant strain energy release rate from 42.72+/-3.65J/m(2) for the controls to 61.35+/-6.26J/m(2). Likewise there was a significant improvement in the strain energy release rate for the gold/composite interface from 27.31+/-3.00J/m(2) to 42.13+/-4.83J/m(2). CONCLUSIONS: Tribochemical technology offers significant potential advantages for clinical dental practice.

Adhesiveness↗

The hardness and modulus of elasticity of primary molar teeth: an ultra-micro-indentation study.

OBJECTIVE: Baseline information on the mechanical properties of and the effect of load upon dental hard tissue is important in the development of successful dental materials. Existing methods of measuring such properties of tissue are subject to significant experimental error. This study reports on the use of an Ultra-Micro-Indentation System (UMIS) to measure the hardness and elastic modulus of primary enamel and dentine. METHODS: Primary molar teeth were sectioned, set in resin and polished. Thirty indentations were made in enamel and dentine using a Berkovitch indentor, 15 of which were subject to a load of 50mN and 15 to a load of 150mN. An automated computerised system converted the force/penetration graph for each indentation in to a hardness vs depth graph from which values for the mean hardness and elastic modulus were calculated. RESULTS: Primary enamel had a mean hardness of 4.88+/-0.35GPa whilst the hardness of dentine was 0.92+/-0.11GPa The elastic modulus for enamel was 80.35+/-7.71GPa and that of dentine 19.89+/-1.92GPa. Using linear regression analysis a significant relationship could be shown between the hardness and the elastic modulus for both enamel and dentine when loaded to 150mN but only for dentine at 50mN (P<0.05). In general the elasticity of tooth structure increased as the hardness increased. CONCLUSION: The UMIS offers a simple and reproducible method of measuring basic mechanical properties of small samples of enamel and dentine.

Child, Preschool↗