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Biomedical subjects

N Kiper

Publications and source records attributed to N Kiper.

43 records · Page 3Linked to original sources

Fiberoptic flexible bronchoscopy via the laryngeal mask airway in children.

The laryngeal mask airway (LMA) is a new device for controlling the airway during many procedures. Aside from its use in different kinds of surgical procedures, fiberoptic flexible bronchoscopy can also be performed easily with this mask in children under sedation. This procedure was performed via LMA in 36 children (aged 2-16 years) who suffered from different kinds of respiratory diseases and were seen at Hacettepe University Ihsan Doğramaci Children's Hospital, Pediatric Chest Disease Unit, during a seven-month period. The procedure was performed with success and no complications occurred. To the best of our knowledge, this is the first report from Turkey on flexible bronchoscopic evaluation via LMA in children with different kinds of respiratory diseases. We suggest that this technique can be used safely.

Adolescent↗

Lipidosis with sea-blue histiocytes. Report of two siblings with lung involvement.

Two siblings, an eight-year-old girl and a three-year-old boy with lipid storage disease, most likely non-neuropathic Niemann-Pick disease (NPD) with sea-blue histiocytes, are presented. Both of them had foamy and sea-blue histiocytes in their bone marrow smears and reticulo-nodular appearance of both lungs on their chest X-rays. Case 1 had diffuse, biopsy-proven, pulmonary involvement associated with sea-blue histiocytes. Although diffuse reticulo-nodular pulmonary infiltration of non-neuropathic NPD (type B) is frequently detected on chest X-rays, to our knowledge there is only one reported adult case of lipidosis resembling NPD in which severe pulmonary involvement associated with pigmented histiocytes and Niemann-Pick cells were demonstrated at autopsy.

Bone Marrow↗

Congenital cystic adenomatoid malformation. A report of a case and review of the literature.

A ten-month-old boy was admitted to our hospital with fever, cough and dyspnea. His history was remarkable for mild respiratory problems from the early neonatal period. Although medical treatment was administered several times in a local hospital, his symptoms recurred. Chest x-ray revealed multiple cystic lesions on the right side. The diagnosis of congenital cystic disease was considered preoperatively, to our knowledge for the first time in our hospital. The patient's postoperative course was uneventful, and no respiratory problems have recurred in 24 months of follow-up.

Cystic Adenomatoid Malformation of Lung, Congenita↗

Osteomyelitis related to BCG vaccination: case report.

A nine-month-old girl with osteomyelitis related to BCG vaccination is presented. The patient did not have any clinical evidence of immunodeficiency. Her X-ray examination showed a lytic lesion of the right tibia and of the left ulna. Histopathological examination of biopsy material revealed a chronic granulomatous inflammatory reaction. She improved with intermittent short course antituberculosis therapy.

Antitubercular Agents↗

Sputum bacteriology and its antibiotic susceptibilities in Turkish cystic fibrosis patients.

To identify lower respiratory tract pathogens and their in-vitro antibiotic susceptibilities in Turkish cystic fibrosis (CF) patients, a total of 383 sputum cultures were evaluated from 45 CF children in 168 symptomatic and 215 control periods over 25 months. Microorganisms were isolated in 252 of the cultures. The isolation rate was 82 percent for symptomatic periods and 53 percent for control periods. The most common microorganism was P. aeruginosa in the symptomatic period and S. aureus in the control period. Other microbiological species included E. coli, H. influenzae, K. pneumoniae, S. epidermidis, beta-hemolytic streptococcus, H. parainfluenzae, K. oxytoca, E. aerogenes and E. aglomerans. P. cepacia was not found. In 20 cultures more than one microorganism was isolated at the same time. In in-vitro conditions, high susceptibility rates were detected to amikacin, ciprofloxacin and ceftazidim for P. aeruginosa; cefuroxime, ceftriaxone, amikacin, cephalothin, chloramphenicol and erythromycin for S. aureus; amikacin and ceftriaxone for E. coli; ampicillin-sulbactam, amoxicillin-clavulanate, cefuroxime, ceftazidime, ceftriaxone and aztreonam for H. influeanzae; and aztreonam and amikacin for K. pneumoniae. Lower respiratory tract pathogens and their antibiotic susceptibilities in Turkish CF children were not significantly different from those indicated previously in the literature.

Adolescent↗

Childhood tuberculosis: a report of 2,205 cases.

A total of 2,205 children with the diagnosis of tuberculosis followed at Hacettepe University Ihsan Doğramaci Children's Hospital between the years 1972 and 1992 were investigated in this retrospective study. Sixty-two percent of the patients were less than six years old. There was no gender preponderance among the cases. Thirty-four percent of the patients had predisposing diseases for tuberculosis, such as malnutrition, measles and pertussis. Thirty-five percent of the patients had a history of contact with a tuberculous patient. The most common type of tuberculosis was pulmonary (39%), but extrapulmonary cases outnumbered pulmonary tuberculosis patients. Thirty-three percent of the patients had been vaccinated with BCG. The Mantoux test was found positive in 62 percent of patients. The tuberculous culture was found to be positive in the sputum of 28 percent of pulmonary tuberculosis cases. Patients were treated with daily (59%) or intermittent (41%) antituberculous therapy regimens. The response to treatment was excellent. Relapse was observed in five cases. Mortality from tuberculosis was eight percent, 23 percent of which were from tuberculous meningitis. Although there was a decrease in the number of children with tuberculosis seen at our hospital between 1972 and 1992, the prevention and control of tuberculosis are still significant health problems for our country.

Adolescent↗

Recurrent pneumonitis in a 10-year-old girl with pigeon breeder's disease.

Hypersensitivity pneumonitis is an allergic disease resulting from sensitization to inhaled organic dust, usually manifest with recurrent bouts of cough, dyspnea and fever. Most of the reported cases concern the adult population. The disease is rarely seen in the pediatric age group, as stated by most of the reviews on the subject. In this article, a case with hypersensitivity pneumonitis is described. Precipitating antibodies to avian protein were demonstrated in serum from a girl with recurrent bouts of pneumonitis which was otherwise unexplained.

Acute Disease↗