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Biomedical subjects

N Krpan-Antonin

Publications and source records attributed to N Krpan-Antonin.

7 recordsLinked to original sources

[Results of the therapy of acute leukemia during 10 years (1972-1982)].

The group of 31 patients with acute leukemia was analysed: 24 ALL and 5 ANLL. The complete remission was achieved in 84% of children. Mortality in induction was high and reached 16%. All recidives occurred with in 24 months from the diagnosis. 15% of patients achieve complete continuous remission (CCR) lasting 2 and more years, the result beeing better in patients treated with more intensive regimen. 53% patients will ALL achieved CCR for 5 and more years. In a small group of patients with ANLL the rate of CR is 60%. Only one girl, with a M 3 form lives more than 20 months.

Acute Disease↗

[Fanconi's anemia in 2 brothers].

Two cases of Fanconi anemia in brothers are described. Reticulocytosis and shortened survival of red blood cells in younger brother were observed. Ethiopathogenesis, therapy and prognosis are discussed.

Anemia, Aplastic↗

[Adenocarcinoma of the colon in a 14-year-old boy].

We report the case of a 14-year-old boy with adenocarcinoma of the colon. The diagnosis was established 3 months following the initial symptoms. The tumor was located in the region of the descending colon and was of Dukes B stage. The patient underwent left hemicoloctomy followed by chemotherapy and irradiation. In the follow-up period of two years the patient has been well. It is concluded that early diagnosis, adequate monitoring of patients by the determination of carcinoembryonic antigen and regular follow-up visits could lead to better prognosis.

Adenocarcinoma↗