[Study of nursing standards based on analysis of nursing duty and the number of personnel. Study at a university hospital].
Explore the source record for details and available documents.
Nursing Care↗
Biomedical subjects
N Kuwabara
Publications and source records attributed to N Kuwabara.
Acute pulmonary embolism resulting from cardiac tumors associated with tuberous sclerosis.
A case report of a neonate with cardiac tumors in association with tuberous sclerosis is presented. The rare complication of pulmonary embolism and its successful treatment by anticoagulation and thrombolytic therapy is described. The treatment of these cardiac tumors is conservative, because the tumors regress spontaneously when the diagnosis is made in infancy. However, embolic event may rarely occur as a complication of cardiac tumors. If the cardiac tumors are treated conservatively, it is important to pay close attention to the occurrence of pulmonary embolism during the follow-up period.
Echocardiography, Doppler↗
Incidence of Paneth cells in colorectal adenomas of Japanese descendants in Hawaii.
The main purpose of the present study was to demonstrate the incidence of Paneth cells in colorectal tubular adenomas of Japanese descendants in Hawaii. Paneth cells were found in 73 of 322 adenomas (22.7%) of Japanese descendants in Hawaii. The incidence of Paneth cells in adenomas located from the caecum to the transverse colon was significantly higher than that of adenomas from the descending colon to the rectum. The same trend of a higher incidence of Paneth cells in adenomas from the caecum to the transverse colon was observed in Japanese descendants and Caucasian residents in Hawaii and in native Japanese. The incidence of Paneth cells in adenomas of Japanese descendants in Hawaii was higher than that of native Japanese, and also that of Caucasian residents was higher than that of native Japanese.
Adenoma↗
High calorie infusion-induced hepatic impairments in infants.
Hepatic impairments have been reported sporadically in infants receiving long-term high calorie infusion. Some characteristic hepatic impairments induced with high calorie infusion at the Juntendo University Hospital, Tokyo, are studied in 18 surgical infants, with discussion of the possible etiology of this complication in the context of high calorie infusion. The hepatic dysfunctions were classified into 3 types by sequential liver function determinations: Type I with a transient and slightly elevated serum transaminase without elevation of alkaline phosphatase; Type II, an elevation of alkaline phosphatase and total and direct bilirubin without elevation of serum transaminase; Type III, a marked and prolonged elevation of aklaline phosphatase, total and direct bilirubin, and serum transaminase. The etiology of these hepatic impairments during high calorie infusion is unknown.
Alanine Transaminase↗
Cystic fibrosis of the pancreas: report of a Japanese autopsy case.
Cystic fibrosis of the pancreas is considered to be rare in the Japanese population. Forty-five cases from the Japanese literature (1951-1983) are reviewed and one autopsy case added. The patient was a 17-year-old Japanese male with recurrent episodes of pulmonary infection. His sweat test was positive (sodium 332 mg/l, chloride 316 mg/l). No particular hereditary trait was identified. Autopsy findings showed cystic dilatation of pancreatic ducts and ductules with mucous hypersecretion. Acini of the pancreas were replaced by fibrosis, while islands of Langerhans remained. These findings were compatible with cystic fibrosis of the pancreas (mucoviscidosis). The lungs showed chronic hypertrophic bronchitis and acute obliterating bronchiolitis. Cystic dilatation and hypersecretion were seen in the esophageal glands, Brenner's glands, and enteric glands. Goblet-cell hyperplasia was seen in the enteric glands. Central fatty metamorphosis and focal bile duct proliferation were seen in the liver. No obvious intralobular cholestasis was present. The epithelium of the gall bladder was highly columnar.
Adolescent↗
IgE production by B-cells stimulated with interleukin-4 and Epstein-Barr virus in patients with elevated serum IgE levels.
Epstein-Barr virus (EBV) and recombinant interleukin-4 (rIL-4) induce IgE production by normal B-cells. We demonstrate here the difference in IgE synthesis in patients with elevated IgE levels and normal control subjects. EBV and rIL-4 induced the synthesis of IgE by surface IgE-negative B-cell precursors isolated by cell sorting. IgE synthesis in normal subjects became apparent in the second week with increasing rIL-4 concentrations, whereas in patients with elevated IgE levels, there was a marked elevation in IgE synthesis without rIL-4 stimulation. We did not observe the presence of DNA rearrangement occurring between IgM and IgE switch regions (S mu and S epsilon, respectively) during switching to IgE isotype in patients with elevated IgE levels. We found that with the limited sensitivity of Southern blotting, this method may not be useful for the study of B-cell populations in which only a small percentage of cells have undergone switching.
B-Lymphocytes↗
Relationship between interferon-gamma, interleukin-4 and IgE production of lymphocytes from hen's egg-sensitive patients.
We measured in vitro interferon-gamma, interleukin-4 and IgE production of peripheral blood mononuclear cells stimulated with ovalbumin. Interferon-gamma in culture supernatants of ovalbumin-stimulated peripheral blood mononuclear cells from hen's egg- sensitive patients with atopic dermatitis was significantly higher than that of healthy children or hen's egg-sensitive patients with immediate symptoms. Furthermore, in patients with atopic dermatitis who were sensitive to hen's egg and patients with immediate symptoms, there was an inverse relationship between interferon-gamma and IgE production (r = -0.535, p <0.05), and significant correlation was found between interleukin-4 and IgE production (r = 0.802, p <0.05). For the above reasons, IgE synthesis of ovalbumin-stimulated peripheral blood mononuclear cells may be suppressed by interferon-gamma in patients with atopic dermatitis. In contrast, in patients with immediate symptoms, interleukin-4 may play a major role in the pathogenesis of increased IgE production.
Animals↗