Exposure of workers to inorganic lead in some small and medium industries.
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Biomedical subjects
Publications and source records attributed to N L Ramanathan.
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While surveying the hygienic conditions in small to medium ceramic industries, it was noted that an acute thermal stress problem existed in kiln unloading operations being performed manually. A more detailed investigation of this problem in four typical ceramic factories confirmed that the thermal conditions imposed severe stress on the workers with WBGT values ranging between 43 and 54 degree C inside the kiln. However, the physiological strain experienced by even the workers who remain inside the kiln for unloading the saggers for 10 min or more at a tiem before coming out for a spell of rest was not excessive, except in a few cases. This suggests that the workers had fortuitously chosen, perhaps by experience, a work-rest schedule which did not prove too strenuous. It is considered that it would be desirable to regulate this operation in each factory on a systematic manner after necessary studies to rationalize the work-rest procedure.
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A total of 31 workers employed in hot work in small-scale foundries, 13 gardeners engaged at light jobs under the sun and 16 sedentary persons were selected after medical screening for a study of the levels of serum enzymes [glutamic oxalacetic transaminase (GOT), glutamic pyruvic transaminase (GPT), lactic dehydrogenase (LDH) and adolase]. Only the LDH values in the foundry workers and gardeners differed significantly from that of the unexposed subjects. A trend of slight increase in activity of these enzymes after exposure was observed, though it was not statistically significant.
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The serum enzyme values (GOT, GPT, LDH and Aldolase) of 13 fit healthy volunteers were determined before and after physical effort of a moderate grade of 3.9 Kcal/min. The pulse rate pattern of the subjects during the exercise of climbing up and down a staircase for 30 minutes and during a 10 minute recovery phase was also recorded. The pulse pattern was in no case in excess of 150 bpm and full recovery was achieved within 10 minutes indicating that the exercise was moderate. The serum enzyme values after the exercise were raised. The difference between the exercise and rest values of the four enzyme activities were significant at the 1% level. It was observed that the raised enzyme activity level dropped to normal levels within 24 hours after the exercise. Large individual variations in the rise of these enzyme levels after exercise were observed and hence it is difficult to quantitate the phenomenon. Consequently the value of serum enzyme levels after the exercise as a practical-index of physiological strain is limited.