Biomedical subjects
Publications and source records attributed to N Leggiadro.
We describe four migraine patients who developed an ischemic stroke during their typical migraine attacks. Cerebral infarction as a possible complication of migraine without aura is discussed. We propose a review of the migraine stroke definition of the International Headache Society.
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Forty-two elderly patients affected by a generic cerebrovascular disease developed a parkinsonian syndrome after prolonged treatment with flunarizine. Following flunarizine withdrawal the extrapyramidal symptomatology remitted slowly and progressively for 12 weeks, leading to the belief that the observed parkinsonian syndrome is directly linked to the chronic use of this compound. Similar side effects are not described in young populations, however. A periodic flunarizine discontinuation in chronically treated subjects aged 65 or more is suggested.
"Enuresis risoria" or "giggle incontinence" is a particular condition characterized by a sudden, involuntary, uncontrollable and complete emptying of the bladder during giggling or hearty laughter. We had under observation a 15-year-old girl affected by this condition. The tests she underwent did not reveal anatomic or functional alterations. We were able to control her symptoms with Imipramine. We can thus assume that laughter reacts as a trigger that activates micturition reflex through the intermediation of the limbic system.
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Endocrine features in 22 women affected by idhyopatic hyperprolactinemia and in ten women affected by prolactin secreting adenoma have been assessed basic levels of FSH, LH, E2, T3, T4, and PRL were evaluated and dynamic tests by GnRH, TRH and bromocryptine were performed prolactin basal value and TRH dynamic test show some value in differentiating hydiopatic hyperprolactinaemia from prolactynomas, but no hormon by itself nor dynamic test show a reliable effectiveness for this diagnosis.