Biomedical subjects

N Lioret

Publications and source records attributed to N Lioret.

25 records · Page 2Linked to original sources

PubMed1984

Plasma amino acid pattern in burn subjects: influence of septicemia.

A comparison of plasma amino acid levels was made between two groups of burn subjects, septic and non-septic. On day 4 after injury, results do not show any differences between patients who later went on to develop sepsis on day 7 and those who remained non-septic. Similarly, no differences between these two groups were discernable on day 7. Thus metabolic variations induced by septicemia do not seem to modify the usual burn-induced amino acid variations; consequently, plasma amino acid determination in burn patients do not appear to predict septicemia.

Journal Article↗

PubMed1984

Effect of enterally administered ornithine alpha-ketoglutarate on plasma and urinary amino acid levels after burn injury.

Eight severely burned patients received 10 grams twice a day of enterally administered ornithine alpha-ketoglutarate. Variations in their plasma and urinary amino acid levels were compared with those from six severely burned control patients. The study covered the period from the fourth day to the twenty-eighth day after injury. Essential differences between the two groups were that plasma ornithine and proline increased until day 13 in the treated group, plasma phenylalanine levels were higher in the control group except on day 13, the peak, on the twenty-first day, in plasma concentrations of valine, leucine, isoleucine, tyrosine, lysine, proline, and ornithine, in the control group was not found in treated subjects, and urinary amino acids were lower on day 28 in the treated group. These results suggest that ornithine alpha-ketoglutarate administration lowered protein catabolism after injury, probably through a process mediated by increased secretion of insulin and human growth hormone.

Adolescent↗

PubMed1982

[Blood cortisol level variations in burn patients and their relation to variations in plasma amino acids. Biochemical study of 19 subjects].

Cortisolemia from burn patients is measured during 28 days. The relation between the cortisolemia and values from 16 plasma amino acids is studied on the fourth and on the seventh day after injury. Cortisolemia is higher in the severely burned patients than in mild injured patients. A correlation between the burn surface area and the cortisolemia is found on day four and on day seven. Cortisolemia is also higher in nonsurvivors than in survivors. Plasma methionine, on day four, and plasma phenylalanine, on day seven, are correlated with cortisolemia. This result suggests that hyperphenylalaninemia results from protein breakdown which is essentially cortisol-mediated. However, cortisol does not seem to have a central place in control of amino acidemia after burn injury.

Amino Acids↗

PubMed1976