Biomedical subjects

N Lyall

Publications and source records attributed to N Lyall.

4 recordsLinked to original sources

PubMed1989

Reliable and realistic approach to sensitivity testing.

Antibiotic testing by Disc was compared with Break-Point method using 535 clinical isolates; Disc sensitivity method was carried out in the routine way using the disc provided by pharmaceutical company. Break-point sensitivity was done by incorporating the substrate into solid medium, the results obtained showed greater resistance by Break-point which appears to be more realistic in the light of indiscriminate usage of antibiotic. The method is simple, cost effective, reliable and realistic (JPMA 39 : 94, 1989).

Anti-Bacterial Agents↗

PubMed1989

UTI: a new approach to its diagnosis.

The incidence of urinary tract infection in our community is studied taking into consideration the indiscriminate and inappropriate use of antimicrobial agents and describing a simple method which could be adopted to evaluate samples of urine for the presence of antimicrobial agents. It reveals that 42.9% individuals were actually on antimicrobial agents and had sufficient levels in their urine to inhibit growth of the most common causative agent of urinary tract infection.

Anti-Bacterial Agents↗

PubMed1989

Neisseria meningitidis storage identification and MIC determination.

The significance Minimum Inhibitory Concentration (MIC) of determination for Meningococci is described and according to the present study a shift in the sensitivity of Meningococcus is occurring, local isolates show higher Minimum Inhibitory Concentration for Chloramphenicol and Azactam. Strains of Meningococcus can successfully be stored in a domestic freezer.

Neisseria meningitidis↗

PubMed1989

Legionella pneumophila: laboratory diagnosis in developing countries like Pakistan.

Three hundred random sputum samples were collected for analysis from cases of mild to severe respiratory infections and screened for Legionella pneumophila by both the culture method and also the direct fluorescent antigen test. In one third of the cases, blood specimen was also collected and screened for Legionella serum antibodies. With the direct fluorescent test it was possible to identify Legionella in 9% of the samples while the culture gave positive results in 4.3% of cases. Diagnostic antibody titers (1:256) were obtained in 12% of the samples while another 12% cases showed serum antibody titers of 1:64 to 1:128. In Pakistan where antibiotics are used extensively, the direct fluorescent examination of sputum samples gives more accurate diagnosis of Legionella cases than the culture method.

Colony Count, Microbial↗