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Biomedical subjects

N M Dobrovol'skiĭ

Publications and source records attributed to N M Dobrovol'skiĭ.

9 recordsLinked to original sources

[Prognostic significance of the determination of carcinoembryonic antigen in the blood of patients with lung cancer].

Correlation analysis of the results of examination of 86 lung cancer patients treated by surgery and methods other than surgery established an inverse relationship between life-span and carcinoembryonic antigen (CEA) level. An analysis using reagents supplied by CEA-IRE-Sorin Company showed that a CEA level in blood in excess of 10 micrograms/l is associated with the most unfavorable prognosis. The degree and rate of CEA excretion are in direct correlation with life-span and provide the most reliable criterion in evaluating the effectiveness of lung cancer treatment.

Carcinoembryonic Antigen↗

[Functional state of the hypophyseal-adrenal system in lung cancer].

The results are reported on studies of the secretion of adrenocorticotropic (ACTH), somatotropic (STH) hormones and cortisol, using a standard set for in vitro diagnosis. A total of 66 patients aged 31--70 (64 males and 2 females) have been examined. Among these patients stage II was noted in 17, stage III--in 31, stage IV--in 18. In 19 of them a peripheral cancer and in 47--central cancer was detected. The data obtained indicate an increased basal level of ACTH, STH, cortisol which is directly dependent on the cancer process stage. The maximum increased level of these hormones was noted in low differentiated cancer of the lung.

Adenocarcinoma↗