Biomedical subjects

N Marén

Publications and source records attributed to N Marén.

5 recordsLinked to original sources

PubMed2001

Tele-ophthalmology for the treatment in primary care of disorders in the anterior part of the eye.

Desktop videoconferencing at 384 kbit/s was used for a trial of tele-ophthalmology consultations between a general practitioner (GP) and an experienced ophthalmologist. Forty-two consecutive patients from St Erik's Eye Hospital emergency ward with disorders in the anterior part of the eye were examined. There was an excellent correlation between the diagnoses made with telemedicine support and those made by the ophthalmologist directly. Subsequently, the GP made 121 eye examinations in two years out of a total of approximately 300-400 examinations at the health-care centre. In the first year the GP examined and treated 45-50% of the cases on his own and 30-50% with telemedicine support. In the second year he treated 55-80% of the cases on his own and 5-35% with telemedicine support. Tele-ophthalmology in primary care appears to be reliable and is likely to be valuable in rural areas, where the distance to an ophthalmologist can be a significant obstacle to satisfactory diagnosis and treatment.

Anterior Eye Segment↗

PubMed1985

Timolol in aqueous humour after topical administration. A pilot study.

The concentration of timolol in aqueous humour after one single drop of timolol ophthalmic solution was studied in 19 patients. Relatively high concentrations were found (mean: 626 ng/ml), but the individual differences were great (range: 0 ng/ml - 2080 ng/ml). Possible explanations are discussed. No detectable levels of timolol were found in plasma (detection level greater than or equal to 1 ng/ml).

Adult↗

PubMed1982

Additive intraocular pressure reducing effect of topical timolol during systemic beta-blockade.

The effect on intraocular pressure (IOP) of topical timolol was studied in 30 patients with arterial hypertension treated with oral alprenolol, metoprolol or timolol. No patient had any known eye disorder. Topical administration of timolol induced a significant reduction of IOP regardless if the patients had systemic beta-blockade or not. Treatment with topical timolol alone was equally effective in reducing IOP as combined topical and oral therapy. Patient compliance was checked with plasma concentrations of the different beta-blockers.

Administration, Oral↗

PubMed1980

Timolol versus pilocarpine separately or combined with acetazolamide-effects on intraocular pressure.

Fifty-eight patients with intraocular hypertension or primary open angle glaucoma participated in a double masked randomized study. Timolol in concentrations 0.25% and 0.5% was compared with 1, 2, or 4% pilocarpine Acetazolamide (250 mg x 3) was added if intraocular pressure (IOP) was uncontrolled with the highest concentrations tested. No statistical difference was found in hypotensive effect between pilocarpine and timolol neither on ocular hypertensions nor glaucomas. The additive hypotensive effect of acetazolamide was the same for both substances. Once a day by administration of timolol was sufficient in 17 of 20 cases controlled merely by topical administration.

Acetazolamide↗

PubMed1980

Timolol-maintenance treatment.

Thirty-eight patients with ocular hypertension or glaucoma were treated with topical timolol for 12-30 months (mean 20). A long lasting hypotensive effect of timolol eyedrops was found. However a need to increase therapy during the follow-up period was noted especially in the glaucoma group. Eyes with pseudoexfoliations often required concomitant therapy from the beginning. Ocular side effects were relatively few but four cases of punctate keratitis and another two with decreased corneal sensitivity were observed.

Aged↗