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Biomedical subjects

N Mock

Publications and source records attributed to N Mock.

9 recordsLinked to original sources
PubMed2002

Iodine fortification is related to increased weight-for-age and birthweight in children in Asia.

Severe iodine deficiency causes stunting and mental retardation in utero, but the relation between mild deficiency and child growth is not well known. The use of iodated salt in relation to anthropometric data was examined from recent survey data. After potential confounding factors had been controlled for, significant associations were seen in Bangladesh, India, Nepal, and Sri Lanka. The use of iodated salt was related to increased weight-for-age and mid-upper-arm circumference, most strongly in the second year of life, mainly affecting soft tissue (thinness). The relation with weight-for-age was greater among children of mothers with lower body mass index. The use of iodated salt was related to birthweight in Sri Lanka and in the Philippines, where iodized oil capsules given during pregnancy had a negative effect when used with high levels of iodine in salt. The associations generally were concentrated in large geographic areas, possibly because of interactions with other environmental factors (e.g., selenium and arsenic). The apparent growth response to iodine may reflect functional effects of mild deficiency, which is widespread, possibly including effects on brain development.

Aging↗
PubMed1998

Measuring hunger in the Russian Federation using the Radimer/Cornell hunger scale.

Compared in the study are the results obtained using the Radimer/Cornell hunger scale to measure the prevalence of hunger in random samples of mothers and their households in the Russian Federation and in the USA in 1993. The 12 items in the scale measured hunger at three levels: household, women, and children. If the mother answered positively to one of the four items at a particular level, hunger was established for that level. The prevalence of hunger in the Russian Federation was very high: approximately 77% of the women surveyed, 70% of the households, and 32% of the children were classified as hungry. The corresponding estimated prevalences of hunger in New York State in 1993 were 46.8%, 25.9% and 18.3%. In both surveys, children were the least likely to be classified as hungry and, if they were, their mothers and households were almost always hungry. In both surveys, the hunger scale proved to have criterion-related validity. Basic indicators of household socioeconomic and demographic well-being were highly related to the three levels of hunger. The higher level of hunger in the Russian survey can be explained by the very low incomes. Further study of the nutritional status of the Russian population is recommended.

Adult↗
PubMed1996

Cultural response to mental illness in Senegal: reflections through patient companions--Part II. Statistical correlates.

Patient records from the Thiaroye Psychiatric Hospital in Senegal were studied to see if analysis of patterns of persons accompanying patients to the hospital could help to portray the community's response to mental illness. A systematic sample of 935 records of initial out-patients visits were examined. Patterns of patient companionship were found to strongly correlate with specific patient sociodemographic and clinical characteristics. Interpretation of these findings helped to clarify both prevailing attitudes toward the mentally ill and the social response and management of mental illness. The first article in this series presented the study setting, methods, sociodemographic and clinical characteristics of the patients, and characteristics of patient companions. The current article examines the statistical associations of companion number, gender and kinship relationship with patient sociodemographic and clinical characteristics.

Adolescent↗
PubMed1996

Health and nutrition in children under 2 years of age in three areas of the Russian Federation.

The study objectives were to determine the nutritional status of children under 2 years of age in selected areas of the Russian Federation, to estimate the proportion of children potentially at risk for nutritional problems, and to characterize such a vulnerable group in terms of demographic variables. A cross-sectional sample of children under 2 years of age was used. Six areas-Moscow, St Petersburg, Ekaterinburg, and their surrounding oblasts-were sampled, and data were collected for approximately 800 children in each area between July and December 1993. A low prevalence of children with a weight-for-age Z-score below -2 was found, indicating that at the time of the survey protein-energy malnutrition was not a serious problem for this age group. However, other survey results indicating high morbidity, low immunization rates, the possibility of food insecurity, and poor infant-feeding practices imply that children's health could easily deteriorate. Therefore, food security and children's nutrition should be monitored to avoid serious consequences in the future. The results also show that there is ample scope for public health interventions that encourage more effective immunization coverage, emphasize prevention of childhood diseases, and promote proper infant-feeding practices.

Adult↗
PubMed1993

Development of information-based planning in Niger.

The authors present their experiences in assisting the government of Niger to develop automated information systems for health care management. They discuss the structure of the health system, the role of donor assistance, the process of initiating automated systems, and the technical requirements and costs of the system. Finally, they draw general conclusions that may be useful for those attempting similar efforts.

Costs and Cost Analysis↗
PubMed1993

Maternal behavioural risk factors for severe childhood diarrhoeal disease in Kinshasa, Zaire.

This study examines the relationship between severe diarrhoeal disease and maternal knowledge and behaviours related to hygiene and sanitation. Some 107 paediatric cases admitted to two hospitals in Kinshasa, Zaire in 1988 were matched on age and nearest-neighbour status to 107 controls. Personal interviews and observational methods were used to assess knowledge and behaviours related to hygiene and sanitation. Cases and controls had equivalent socioeconomic status, demographic profiles and access to water and sanitation facilities. However, cases generally exhibited lower levels of knowledge and less sanguine sanitary practices than did controls. Of particular interest was the finding that very specific behavioural items distinguished cases from controls. The disposal of the child faeces and household garbage and mother's knowledge that poor caretaker cleanliness was a cause of diarrhoea in children showed the strongest associations with risk of diarrhoea. There was an exponential relationship between the number of these items a mother answered incorrectly and the odds of diarrhoeal disease. The risk attributable to these three variables was as high as 70%. These findings provide further support for the view that focused educational interventions may have a substantial impact on the occurrence of severe diarrhoeal disease in low-income countries.

Adult↗
PubMed1980

Perinatal developmental changes in hepatic UDP-glucuronyltransferase.

Postnatal developmental changes in hapatic microsomal UDP-glucuronyltransferase were studied in the rat. The previously reported postnatal decline in the capacity of microsomal fractions to glucuronidate p-nitrophenol was found to be observable in unperturbed preparations only at non-saturating concentrations of the substrate UDP-glucuronic acid. At saturating concentrations of UDP-glucuronic acid, activity is identical in newborns and adults. Kinetic analysis revealed that the enzyme from liver of newborns has a much higher affinity for UDP-glucuronic acid than does the enzyme in adults, but the same activity at Vmax. On the other hand, the enzyme from adult liver microsomal fractions can be activated by the physiological allosteric effector UDP-N-acetylglucosamine, whereas the enzyme from newborns is largely unaffected by it. Thus it appears that the number of enzyme active sites is not changing; rather, the enzyme is maturing to a more highly regulable form. There were also differences between the enzymes in newborns and adults in their response to perturbation of the membrane-lipid environment by detergent and phospholipase A. Possible interpretations of these differences are discussed.

Aging↗