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Biomedical subjects

N N Bazhanov

Publications and source records attributed to N N Bazhanov.

At least 19 recordsLinked to original sources
PubMed2006

[Use of miramistin for the treatment of patients with odontogenic phlegmons in the maxillofacial area].

In experimental and clinical conditions the use of miramystin (0.1% solution and liniment) was validated for complex treatment of patients with odontogenic maxillofacial phlegmons (110 patients with mild, moderate and severe inflammation). Significant efficacy of a wide spectrum antiseptic (miramystin) and laser fluorescent diagnostic method for achievement of objective assessment of the treatment of patients with phlegmons in maxillofacial area is shown. The disease duration (time from its onset till discharge from the hospital) varied from 8.2 to 24.1 days depending upon the degree of severity of the inflammatory process versus 13.7 to 30.4 days in controls, respectively. The developed treatment-and-diagnostic methodology is recommended for wide clinical practice.

Administration, Topical↗
PubMed2003

[Laser fluorescence in assessing the hygienic status of oral cavity].

The issue related with an objective evaluation of a hygienic status of the oral cavity and a method to solve it by modern laser technologies are addressed in the paper. The efficiency of bacteriological and of laser-fluorescence express-diagnostics is comparatively analyzed. A hygienic index and its clinical value are substantiated.

Bacteria↗
PubMed1999

[Problem in the diagnosis of anaerobic infections and dysbacteriosis in clinical dentistry].

The fluorescence technique was proposed for rapid diagnosis of anaerobic infection. It determines the microbiocenosis of a wound, the gastrointestinal tract, maxillofacial region, and other pathologically changed organs and tissues. The technique allows one to follow the time course of changes in the microflora and in the pathological process during the treatment and follow-up of a patient. An attempt was made to establish a rapid diagnosis of intestinal dysbacteriosis and to evaluate its severity. A real-time feed-back unit was developed for the diagnosis of anaerobic infection. An anaerobic microflora model in dental caries was used to work out criteria for the informative value of the proposed technique and it was clinically tested.

Bacteria, Anaerobic↗
PubMed1998

[A method of preparing a transplant for eliminating defects and deformities in the supporting facial tissues].

A method for making transplants for repair of abutment tissue defects and deformations based on computer technology is proposed. The technology unites surgical treatment, clinical and x-ray computer-aided diagnosis, computer processing of information and models, experiments, and production. Correspondence of the implant to repaired structures, site of implantation, and individual defect was confirmed experimentally [5], clinically [10], and by control computer-aided tomography. For the first time an implant was made by computer technology, identical to abutment tissue defect, and a method for plastic repair of defects and deformations in the skull by individually prepared implants developed and realized under clinical conditions.

Biocompatible Materials↗
PubMed1998

[Cardiac rhythm and conduction disorders in polymyositis and dermatomyositis].

To assess condition of the heart in polymyositis (PM) and dermatomyositis (DM) in terms of defects in the rhythm and conductivity, we carried out ECG, 24-hour ECG monitoring, EIA measurements of KPK MB-fraction and myoglobin, echocardiography and Doppler echocardiography. Maximal frequency of arrhythmia presenting as supraventricular and ventricular extrasystole occurred in patients with acute PM/DM. Blockade of the bundle of His left anterior branch was detected most frequently in patients with acute and subacute PM-DM and in those with high serum levels of KPK MB-faction and myoglobin. Frequency of rhythmic and conductivity disorders seems unrelated to the disease duration. We registered no alterations at rest either in intracardiac hemodynamics or myocardial contractility. The study of these parameters under exercise test may provide objective information on early defects in myocardial contractility.

Adolescent↗
PubMed1996

[Microecology of non spore-forming anaerobes in health and in disease].

The authors studied the species-specific and quantitative composition of the large intestinal microbiocenosis on exposures to various factors of endo- and exogenous etiologies: the presence of a pathological process and its specific features, dietary trace element composition, unfavorable environmental (chemical) factors, as well as the impact of coexistence in the same family and the factors of family variability (the individual genotype of the macro-organism). The microenvironment of non spore-forming anaerobes that colonize the large bowel was found to be influenced by a number of various factors, both exo- and endogenous. The magnitude of these changes is associated with the intensity and specificity of an influencing factor.

Animals↗
PubMed1996

[The use of immunological indices for assessing the severity of the course of periodontitis and treatment efficacy].

The authors studied immunological status of patients with paradontosis. If included estimation of extended structure of lymphocytes and functional status of thymus. There was marked correlation between clinical of patients and immunological indices especially in severe form of paradontitis. As immunological preparation T-activin was used in injections and applications. Using of T-activin gave positive results in patient developed of paradontitis.

Adjuvants, Immunologic↗
PubMed1996

[Tactivin in the combined treatment of acute inflammatory diseases of the maxillofacial area].

Examinations of 46 patients with acute inflammatory diseases of the maxillofacial area revealed a reduction of some immunity parameters. Thymic activity of the saliva and blood was found to reduce still more after surgery (opening of the phlegmon). The ratio of thymic activities of the saliva and blood may be an indirect evidence of a tendency in development of an inflammatory process. The authors demonstrated the efficacy of correcting immunity parameters by tactivin, which was particularly effective in grave cases. Tactivin concentrations in the blood and saliva, their time course and ratio may be considered as additional criteria for assessing the status of patients and the risk of complications.

Acute Disease↗
PubMed1994

[Pathogenesis of anemia in systemic scleroderma].

The paper reports a case of anemia with complicated genesis in a male patient with systemic scleroderma (SS). Antianemia therapy was not easy, as after rapid disappearance of iron deficiency vitamin B12 deficiency remained, hemolytic component of the disease persisted. The case demonstrates that multicomponent pathogenesis of anemic conditions is possible. This must be taken into consideration when planning therapeutic policy in SS.

Adolescent↗