[Nikolaĭ Nikolaevich Petrov].
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Biomedical subjects
Publications and source records attributed to N N Blokhin.
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The paper discusses the results of treatment of 102 cases of locally-advanced malignant tumors of the head and neck. Myocutaneous flaps including m.m. platysma, sternocleidomastoideus, trapezius and pectoralis major were used to rectify primary postexcisional defects. Preoperative radiation treatment (30-100 Gy) was given to 92 patients. Primary reconstruction for defects of the head and neck failed to stimulate recurrence development or affect survival as compared to controls. Frequency of complications involved in the said method proved lower while stay at the hospital shorter as compared to other reconstructive procedures. The above method assured a shorter period of rehabilitation and thus saved funds.
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The study was based on the data obtained from a long-term follow-up of 2840 cases of various surgical pathology of the stomach, gastroscopic examination of 1112 surgically-treated patients, experiments on stomach carcinogenesis, clinical and experimental studies on lymph drainage pathways and analysis of the results of 296 radical operations for cancer of the gastric stump. The following aspects of research in cancer of operated stomach were suggested: (1) risk of cancer development in operated stomach; (2) factors contributing to tumorigenesis; (3) biologic peculiarities of growth of gastric stump tumors as well as lymph drainage pathways, and (4) organization of follow-up and development of methods for diagnosis and treatment of the said pathology. The results of the study outlined vistas in prevention of cancer of the gastric stump. Adequate methods of diagnosis and treatment of this grave pathology were developed which was followed by a decrease in postoperative lethality and in increase in 5-year survival rate--to 8.5 and 26.4%, respectively.
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