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Biomedical subjects

N N Kuznetsov

Publications and source records attributed to N N Kuznetsov.

At least 19 recordsLinked to original sources
PubMed1992

[Blood platelet as a test system in the evaluation of neurohormonal imbalance in pregnant women with diabetes mellitus].

A study was made of platelet alpha 2- and beta 2-adrenoreceptors stimulated by adrenaline and alupent as well as of hemostatic system parameters the levels of ACTH, cortisol, glucagon and C-peptide in the blood of women with type I diabetes mellitus during pregnancy, surgical delivery, and the postoperative period. It is shown that the changes in the sensitivity of both subtypes of platelet adrenoreceptors are closely related to the activation of the stress-realizing systems and may serve as a test for estimating the intensity of neurohumoral imbalance both during pregnancy and surgical intervention. The sensitivity of platelet adrenoreceptors to agonists may be examined by a simple retention test allowing rapid information to be derived, which is of paramount importance under clinical conditions.

Adrenocorticotropic Hormone↗
PubMed1991

[Phasic changes in the functional activity of alpha2- and beta2- subtypes of platelet adrenergic receptors--objective criteria of adrenoreactive imbalance in the evaluation of severity of nephropathies in pregnancy].

The pregnant suffering from nephropathies were found to have autonomic nervous control disorders closely related to the major platelet vascular and plasma hemostatic, hemodynamic, and microcirculatory parameters. A combined examination of the macro- and ++micro-hemodynamics and status of adrenoreactive structures assessed the adaptation of a pregnant to nephropathy and her reserve potentialities. Adrenoreactive structure derangement is a measure of the severity of nephropathy. Abnormalities along the whole vasculature are characteristic of dysadaptation.

Blood Platelets↗
PubMed1975

[Work capacity of patients with dumping syndrome after stomach surgery].

Of 528 patients subjected to radical operations on the stomach for cancer, polyposis and ulcerous disease the dumping-syndrome was revealed in 74 patients. Following resection of the distal gastric portion the latter was observed in 49 cases, after resection of the cardia--in 18, and after gastrectomy--in 7. In most patients with the dumping-syndrome an impairment of basic hepatic functions and motor-evacuative function of the gastric stump was observed. The study of the work capacity in patients with the dumping-syndrome has deomonstrated its reduction in most patients (in 74% of cases). 55 of 74 investigated patients proved to be invalids of the second and third group. The capacity for work was mostly impaired in patients showing the dumping-syndrome of average and severe gravity.

Adult↗
PubMed1975

[The work capacity and working arrangements of patients following stomach resection for cancer].

In 282 patients, subjected to gastric resection for cancer, the working capacity was examined according to the data of the Medical Expertise within different terms after surgery. It was found that most of patients in primary examination were acknowledged as disabled workers of the first and second group (70.1%). A dynamic follow-up of patients in late postoperative periods revealed a tendency toward an improvement of their working capacity in a group of patients previously considered as totally disabled. However, in terms over 5 years following the operation more than half of patients proved to be disabled. A comparative estimation of the working capacity in these patients according to the Medical Expertise and personal authors' data has revealed a discrepancy between the group of disability and the work accomplished, i.e. a considerable number of patients, considered as group II, resumed their former activities (as prior to surgery) or did easier jobs. This discrepancy seems, to a certain extent, to be the result of underestimation of the patients' state by the Medical Expertise Commission and overrating the group of disability in them.

Adenocarcinoma↗