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Biomedical subjects

N N Mezinova

Publications and source records attributed to N N Mezinova.

At least 19 recordsLinked to original sources
PubMed1992

[Endometrial Chlamydia infection in women with habitual abortion].

Endometrial, endocervical, and urethral specimens were obtained from 16 nonpregnant women with a history of habitual abortions. Chlamydia were isolated from the endometria of 4 women, but only in one case chlamydial intracytoplasmic incorporations in endometrial cells were detectable by the Romanovsky Giemza staining. Endometrial Chlamydia infection was diagnosed in 5 of the 16 patients. No Chlamydia were isolated from the cervix uteri or urethra of 2 patients with endometrial involvement. The study has demonstrated that eradication of intrauterine chlamydial infection before pregnancy improves the efficacy of treatment of habitual abortions. It is possible that asymptomatic chlamydial endometrial infection is injurious for the placenta.

Abortion, Habitual↗
PubMed1989

[Urogenital chlamydia infection in women with habitual abortion].

The Chlamydozoan population was identified in 43.6 per cent of 110 females with a history of habitual abortion. It was found that the infection was more frequent in females aged under 30 years, in those who was born preterm, in patients with early (premarital) sexual contacts or those with spontaneously stopped pregnancy during the first trimester, as well as in those females who suffered from cervicitis, yeast colpitis, pyelonephritis or had post-inflammatory changes of placental tissue. Higher incidence of cervicitis, cervical erosion, yeast colpitis, salpingo--oophoritis and pyelonephritis was documented in females infected with Chlamydozoa.

Abortion, Habitual↗
PubMed1980

[Cellular immunity indices in benign breast tumors].

Patients with breast cancer, localized fibroadenomatosis and healthy females were examined for the initial state of cell immunity: the reaction of delayed hypersensitivity to DNCB, the absolute and relative amount of rosette forming cells (T-lymphocytes) and the stimulation of lymphocytes under exposure to PHA. A considerable suppression of cell immunity was shown both in breast cancer patients and in patients with benign tumors. The indices of skin allergic test and reaction of spontaneous rosette formation were nearly identical in both groups of the patients under examination. In case of the reaction of lymphocytes blasttransformation in breast cancer patients the stimulation was found to be much lower than in patients with local fibroadenomatosis.

Adenofibroma↗
PubMed1979

[Use of hormone loading tests for assessing the source of hyperestrogenism and the functional state of the ovaries in breast cancer patients in menopause].

The source of hyperestrogenia was ascertained in 12 patients by dexametasone-infecundin test, and the ovarian hormonal activity in 5 patients by dexametasone-choriogonin test. The source of hyperestrogenia was found to be the adrenal glands in 50%, ovaries--in 30% and the adrenal together with ovaries--in 20%. Ovarian hormonal activity was retained in 3 of 5 patients under examination. The response to the test concerned was changed in two of them. It is felt that application of hormonal stress tests will make it possible to get detailed indications to castration in menopausal patients with breast cancer.

Adrenal Glands↗
PubMed1975

[Hormonal correlations in hyperplasia of the breasts in women with ovulatory cycles].

An excretion of the follicle-stimulating hormone (FSH), estrogens, pregnandiol, 17-KS, vaginal cytology were studied in 22 patients with dyshormonal hyperplasias of mammary glands and in 12 healthy females with ovulatory cycles. The age of patients under study ranged from 20 to 49 years. The patients showed a higher level of excretion of FSH, estriol, pregnandiol and a lower level of 17-KS excretion than healthy persons.

17-Ketosteroids↗