PubMed Health⌕ Search

Biomedical subjects

N N Nikolaenko

Publications and source records attributed to N N Nikolaenko.

At least 19 recordsLinked to original sources

[Reflection of evolutionary trends in the recovery pattern of the electrical activity in the human brain after unilateral electroshock].

After unilateral electroshocks the following stages of the recovery of EEG may be defferentiated in man: residual seizure activity, flat EEG, low-amplitude polyform arrhythmia, monoform delta-rhythm, synchronized teta- and alpha-rhythms. It is assumed that changes of these stages reflect the migration of EEG pacemakers within the system of hierarchically interrelated brain structures, which provide for various forms of regulation of the electrical activity of the cortex. It was shown that in each of the hemispheres, pacemakers operate relatively independently and that electrical stimulation of the dominant (left) hemisphere affects brain activity to a greater extent than stimulation of nondominant (right) hemisphere. The ascending influences of desynchronizing systems of the brain stem are less lateral as compared to the ascending pathways of hypothalamic and thalamic structures.

Biological Evolution↗

[Functional brain asymmetry and changes in the structure of the visual space in emotional pathology and psychotropic exposures].

By means of graphic test (drawing on irregular grid) the preference of the space parts by patients in depressive and maniac states and also after the injection of psychotropic agents (antidepressants and neuroleptics) was studied. In depression and also after the injection of neuroleptics such modus of graphic test execution was revealed which can be conditionally determined as integral structuring of the space with the preference (high actuality) to its left part. The proofs are given that such type of test execution is typical for predominance of activation of the right hemisphere over the left one. In the manic state and after administration of improving mood drugs, a quite different type of grid filling is revealed, which is determined as fractional structuring of space with a decrease of actuality of its left part. Such type of space representation is typical for predominance of activation of the left hemisphere over the right one.

Affective Symptoms↗