N N Zhilkova | PubMed Health

PubMedDate not supplied

[Clinico-morphological characteristics of surgically removed thyroid gland of the residents of Primorskii territory].

The authors carried out a histological study of 150 thyroid glands removed for various forms of goiter. Nodular and mixed goiter with frequent signs of degeneration prevailed in residents of the Primorsk region. Histological structure of the majority of them corresponded to the colloidal, mostly to the macrofollicular goiter. A lower percentage of morphological signs of the goiter activity in comparison with the clinical data revealed in the hospitalized patients can be attributed to the efficacy of antithyroidal therapy causing involution of the hyperactive glands. Various types of adenomas chronic thyroiditis and the initial stages of the node malignization were determined only by histological examination.

Adolescent↗

PubMedDate not supplied

[Post-thyrotoxic arterial hypertension].

The paper is concerned with the results of a study of the state of central hemodynamics, sympathetic-adrenal and renin-angiotensin systems to reveal their role in the development of postthyrotoxic arterial hypertension. Altogether 147 patients with diffuse toxic goiter before therapy and 114 patients after surgery (subtotal subfascial thyroidectomy after O. V. Nikolaev or its modification) were investigated. In 35 (30.7%) of 114 operated on patients BP values in the long-term postoperative period were above 160/95 mm Hg. Hemodynamic indices and the state of the vasoactive system were correlated. In the authors' opinion, raised activity of the sympathetic-adrenal and renin-angiotensin systems observed during decompensation of diffuse toxic goiter and progressing after surgery, led to the transformation of central hemodynamics of the hyperkinetic type into the hypokinetic one, causing the development of postthyrotoxic arterial hypertension.

Adolescent↗