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N N Zhukov-Verezhnikov

Publications and source records attributed to N N Zhukov-Verezhnikov.

4 recordsLinked to original sources
PubMed1977

[Role of substrate inductors in the mechanism of cortisol action on beta-galactosidase activity in different strains of E. coli k-12 and in rat liver].

A comparative study of the effect of cortisone on the beta-galactosidase synthesis in E. coli K-12 strains with an induced (E. coli 200 PS/Iac), constitutive (E. coli ML-308), and superrepressed (E. coli 200is) type of the enzyme synthesis and in the cells of rat liver demonstrated that the hormone proper had no derepressive effect. An increase of the beta-galactosidase synthesis occurred only in the presence of specific substrate inductors. It is supposed that the principal link in the action mechanism of cortisone on the laclose operon of E. coli and the enzyme production in the cells of the rat liver is preliminary derepression of the genome areas by means of the substrate inductors.

Animals↗
PubMed1977

[Conduct of Bacillus subtilis transformation in mice under conditions of immunologic suppression of exogenous DNAase 1 activity].

Bacillus subtilis transformation was conducted in the abdominal cavity of mice. The frequency of transformation was considerable decreased when bovine DNA-ase 1 (3-- 5microgram) was injected intraperitoneally to these animals. Immune rabbit gamma-globulins containing antibodies to bovine DNA-ase 1 inhibited in vivo the activity of DNA-ase 1, protected transforming DNA from the hydrolyzing effect of this enzyme. This model can be utilized in search for ways to preserve DNA injected into the animal organism for the purpose of genetical engineering.

Animals↗