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Biomedical subjects

N Nimphius

Publications and source records attributed to N Nimphius.

6 recordsLinked to original sources
PubMed1995

Antibiotic therapy and the anesthesiologist.

The anesthesiologist is frequently responsible for administering antibiotics in the immediate preoperative and intraoperative periods. Anesthesiologists often are not trained in the administration of antibiotics, which can be associated with both acute and long-term complications including potentiation of neuromuscular blocking agents, allergic reactions, and end-organ toxicity. The indications for perioperative antibiotics, proper method of administration, and occurrence and treatment of major side effects of the more commonly recommended prophylactic antibiotics are discussed.

Anesthesia↗
PubMed1992

Anesthetic drugs and emergency departments.

Hospital emergency departments were surveyed on their use of N2O, intravenous anesthetics, and neuromuscular blocking drugs; patients monitoring during their use; and the monitoring and evaluation of the quality and appropriateness of the use of these drugs. We received 90 of the 170 surveys sent for a response rate of 53%. Sixty-three percent of the emergency departments that answered our survey administer one or more of these drugs in the emergency room. Less than two-thirds of these respondents indicated they use patient monitors while administering these drugs. The emergency department monitors and evaluates the appropriate use of these drugs in about half of the hospitals that use them, whereas the anesthesiology department is involved less than 20% of the time. Anesthesiology departments should become more involved in developing criteria for evaluating the quality of anesthesia administered by other hospital departments to help ensure that all patients receive a comparable level of anesthetic care throughout the hospital.

Data Collection↗
PubMedDate not supplied

Diaphragm dysfunction and respiratory insufficiency after upper abdominal surgery.

This study was designed to determine the contribution of diaphragm dysfunction and pain to respiratory insufficiency after upper abdominal surgery. Respiratory insufficiency and postoperative pain in humans were evaluated by pulse oximetry, pulmonary function tests, and a visual analog scale. Diaphragm shortening in dogs was evaluated with biplane videoroentgenography. In humans, despite reasonable pain control, pulmonary function, as reflected in forced vital capacity (FVC), forced expiratory volume in one second (FEV1) and arterial oxygen saturation (SpO2) were significantly reduced on the first postoperative day. Improved pain control was not associated with improvements in FVC or FEV1. In the dogs, diaphragm shortening and tidal volume were significantly reduced in the immediate postoperative period. Phrenic nerve stimulation immediately after surgery resulted in supramaximal diaphragm shortening, which indicated neither the diaphragm nor phrenic nerves were significantly injured by surgical manipulation. Diaphragm dysfunction has a major role in postoperative pulmonary insufficiency; an afferent-mediated reflex inhibition of the phrenic nerves may be responsible.

Abdomen↗