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Biomedical subjects

N O Nikolaev

Publications and source records attributed to N O Nikolaev.

At least 19 recordsLinked to original sources

[Gastric leiomyomas].

Leiomyomas are rare tumors found as a rule in the stomach (1-2% of all gastric tumor cases) and occasionally in the intestine. Unless they grow large or become ulcerated gastric leiomyomas run a silent course. Otherwise there is epigastric pain, hemorrhage or impaired gastric evacuation. When complicated, the disease presents diagnostic difficulties and is treated surgically. Gastrotomy with dissection of the tumor or local resection of the gastric wall proved a reliable therapeutic means. Gastric resection is indicated in ill-defined tumors or in suspected malignancy.

Adult↗

[Intraoperative injuries of the spleen].

Operations for gastric and duodenal ulcers were performed in 1123 patients. Injuries of the spleen were found in 16 patients. Attention is called to special care necessary during manipulations on the upper part of the stomach.

Electrocoagulation↗

[Surgical treatment of patients with giant stomach ulcers].

The authors analyse 59 cases with giant gastric ulcers (measuring 3 cm or more in diameter) treated by surgery, which accounted for 10.7% of all the operations conducted for gastric ulcers. It is shown that giant gastric ulcers are complicated and recur most frequently. Planned operations were performed on 56 patients, 3 patients underwent emergency operations at the peak of hemorrhage, the stomach was resected in all of them. Total postoperative mortality was 3.4%, no fatal outcomes occurred in emergency operations. The authors conclude that giant gastric ulcers should be treated by operation after 2-3-week course of preoperative management. Resection of the stomach is the operation of choice.

Adult↗

[Characteristics of diagnosis and surgical treatment of giant gastroduodenal ulcers].

Out of 1364 patients operated on in the Central Research Institute for Gastroenterology for ulcer, 130 (9.53%) appeared to have giant gastroduodenal lesions. The latter were gastric in 59 patients (more than 3 cm in diameter), duodenal in 71 (more than 2 cm in diameter). Surgical treatment of the giant ulcers is a valid therapeutic measure in view of frequent complications, uneffective conservative treatment, common recurrences. Billroth I gastrectomy was performed in 2 patients. Billroth II gastrectomy in 110 with additional bilateral subdiaphragmatic or selective vagotomy in 8 cases, Roux' operation in 2 patients. Gastroenteroanastomosis was established in 16 cases of inflammatory infiltrate, disturbed gastric evacuation, no evidence of hemorrhage from the ulcer; in 15 cases of truncal bilateral subdiaphragmatic vagotomy. Lethality reached 3.07% (4 patients), which is a relatively low rate achieved due to appropriate preoperative preparation and early surgical intervention.

Adult↗

[Reconstructive surgery of peptic ulcer and ulceration of the gastroenteric anastomosis].

An experience with treatment of 177 patients has shown that peptic ulcers are a severe pathology with a pronounced pain syndrome and early development of complications. They are subject to operative treatment after thorough examination and a course of antiulcer therapy during 4-5 weeks before operation. Reconstructive resection of the stomach in combination with truncal vagotomy is thought to be most radical for peptic ulcer. Lethality after reconstructive operations was 5.5%. Trophic ulcers of the gastrointestinal anastomosis is subject to operative treatment but in cases of the presence of other postresection disorders requiring surgical treatment.

Adult↗

[Biliary ascites and biliary peritonitis].

Questions concerned with the penetration of bile into the abdominal cavity are discussed. The observation of 9 patients was used. The effusion of infected bile into abdominal cavity results in the development of bile peritonitis requiring urgent surgical measures. If the bile is not infected, bile ascites is developing, its clinical picture being obliterated and the patients often remaining in satisfactory condition for a long time.

Adult↗