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Biomedical subjects

N O Steiner

Publications and source records attributed to N O Steiner.

3 recordsLinked to original sources

Effects of drugs, age and illumination on response speed of squirrel monkeys.

Four young (2 1/2 years) and four older (over 10 years) squirrel monkeys were used to study age differences in the effects of d-amphetamine, methylphenidate and illumination on response speed. Although young monkeys were faster than the old monkeys, only the older monkeys showed an illumination effect. Both d-amphetamine and methylphenidate slowed response speed but only in the older monkeys showed an illumination illumination was present. These results suggest that older, mature squirrel monkeys are more sensitive to the effects of d-amphetamine, methylphenidate and illumination than young squirrel monkeys.

Age Factors

Effects of d-amphetamine and methylphenidate upon auditory threshold in the squirrel monkey.

The effects of d-amphetamine sulfate and methylphenidate hydrochloride on auditory thresholds in ten squirrel monkeys were examined using a 4.2 kHz stimulus in a free field. The results indicated that d-amphetamine raised auditory thresholds but methylphenidate did not alter the thresholds. The elevation of sensory thresholds by d-amphetamine was in agreement with previous studies suggesting that the drug acts as a behavioral depressant in diurnal animals.

Animals