Efficacy of narrowband UVB phototherapy in early stage of mycosis fungoides.
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Biomedical subjects
Publications and source records attributed to N Onsun.
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Mycosis fungoides is the most common type of cutaneous T-cell lymphoma. The extent and type of skin involvement (T classification) and presence of lymph node or visceral involvement are important predictors in selecting the type of treatment. Skin directed treatment represents the most appropriate therapy for early stage disease. Current topical treatment including potent topical steroids and nitrogen mustard are associated with adverse effects such as cutaneous atrophy and contact dermatitis. In the present study, we tested the efficacy of imiquimod in mycosis fungoides plaques.
Spitz nevus is most commonly a benign solitary lesion. Agminated or disseminated Spitz nevi represent an uncommon manifestation of this nevus. We report an unusual case of Spitz nevi arising and disseminating during pregnancy.
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BACKGROUND: Pediculosis capitis is a worldwide problem. We studied the prevalence of this infestation in Istanbul. METHODS: We reviewed the records of the Dermatology Clinic of Istanbul University Cerrahpaşa Medical Faculty from a 20-year period (1970-1989). RESULTS: The number of cases of pediculosis capitis have gradually increased over this period, with a peak in 1981. Women are more involved than men. There has been a significant increase in cases in children of school and pre-school ages. CONCLUSIONS: Many factors may have contributed to this increase: poor hygiene and socioeconomic conditions, lack of medical training, and probably some resistance to pediculicide preparations in the lice. The stigma attached to the disease may prevent people from coming forward.
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Mycosis fungoides is very rare in children. Hypopigmented lesions of this disease are usually observed in dark-skinned individuals and often show a T supressor CD8(+) phenotype. Two Caucasian children with predominantly hypopigmented lesions of mycosis fungoides are presented here. Atopy was a concomitant feature in both.