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N Ortego Centeno

Publications and source records attributed to N Ortego Centeno.

At least 19 recordsLinked to original sources

[Virus and systemic vasculitis].

The participation of genetic and environmental factors has always been invoked in the pathogenesis of the autoimmune systemic diseases, including the primary vasculitides. Among the environmental factors, infections, fundamentally those having a viral nature, have always been focused on, especially after the discovery of the close existing relationship between the polyarteritis nodosa and the hepatitis B virus, on the one hand, and mixed cryoglobulinemia and the hepatitis C virus, on the other. The present review summarizes data from the most recent literature related to associations between virus infections and primary vasculitides, following the Chapel-Hill vasculitis classification.

Humans↗

[Internet application for medical purposes in chronic patients cared in a systemic autoimmune diseases unit].

OBJECTIVE: In recent years Internet has become an important tool for medical information search, not only for physicians but also for the patients. Little is known about Internet patient's use in Spain. Our objective was to study the frequency with which patients with different chronic autoimmune diseases cared in our unit use Internet as a source of medical information, and to identify the factors associated with its use. METHODS: A survey was carried out on Internet use to patients cared in a teaching hospital Systemic Autoimmune Diseases unit along three consecutive weeks. RESULTS: Hundred thirty-eight patients completed the questionnaire. Eighty-seven (63%) were women. Fifty-four patients (39.1%) were older than 55 years. Mean disease progression was 34.2 +/- 39.2 months. 22% of the respondents were uneducated, 39% had elementary education level; 20% had average education level, and 20% had advanced education level. Forty-two patients (30.4%) used regularly Internet for any purpose. Factors associated to Internet use for medical purposes were regular Internet use (OR: 4.6; CI: 1.1-18.8;p = 0.03), and average or advanced educational degree (advanced education: OR: 22.9; CI: 2.6-202.7; p = 0.005; average education: OR: 8.5; CI: 1.2-59.6; p = 0.03). Eighty-one patients (58.7%) expressed their need of information on quality web pages. CONCLUSIONS: Many patients use Internet for medical purposes in our environment and even more consider to use it in the future. It is important to be aware of this fact and facilitate information about quality web pages for interested patients.

Adult↗

[What is the opinion of Spanish internists on osteoporosis?].

OBJECTIVE: To conduct an opinion survey on osteoporosis in Spanish internists. METHOD: Survey sent by mail and by personal visit to members of the Spanish Internists Society. Collection of data on opinion on the disease, diagnostic and therapeutic attitude and means available (general laboratory analyses, conventional radiology, biochemical markers of bone remodeling, densitometry and ultrasounds) and preference when choosing a certain treatment. RESULTS: A total of 538 internists answered. More than 90% of those surveyed consider that osteoporosis is a disease that should be treated by internists. A total of 93% consider that osteoporosis is a prevalent disease. More than 80% have access to densitometry. CONCLUSIONS: The majority of Spanish internists consider that osteoporosis is a disease that should be treated by internists and that it is a disease that enters into their action scope. In general, they have the means necessary for its study and treatment. Bisphosphonates constitute the drug of choice and calcium and vitamin D supplements are indicated in almost all the cases.

Aged↗

[Prescription of generic pharmaceutic specialties in discharge reports at a university hospital].

BACKGROUND: The use of generic pharmaceutic specialities (GPS) has risen lately as a necessary tool in the control of sanitary expenses. This use is becoming of high importance, even in the non-medical media. Our aim was to stablish its use profile in patients discharged from a University Hospital. MATERIAL AND METHOD: To analyse the use of GPS in 256 discharge reports, randomly chosen from the Clinical Documentation Service, belonging to eight different Units for two months (June-July 2000). RESULTS: A total of 1233 prescriptions were reported. Among them, there was an equivalent generic drug to the medication prescribed in 220 cases (18%), but only in five ocasions one of them was indicated (2.2%). The cost of the drugs with an equivalent form in GPS was calculated in 707,521 pts. This cost could have been reduced to 505,865 pts. taking into account the average price of the GPS. In case of indicating the cheapest one, the cost could have been 479,672 pts. CONCLUSIONS: There is an important proportion of GPS to indicate as an alternative to the usual medicaments prescribed. However, nowadays, the GPS prescription is not a usual practice among the hospital physicians.

Adolescent↗

[Serum 1,25-dihydroxyvitamin D in insulin-dependent diabetes mellitus].

To evaluate the relationship between insulin and hormonal vitamin D system we compared the serum concentrations of 1.25 dihydroxyvitamin D (1.25 D) in a group of 56 patients with insulin dependent diabetes mellitus (IDDM) with those from a control population of 26 healthy individuals. We did not find overall significant differences in 1.25 D levels between diabetic patients and control individuals (32.6 +/- 12 vs 35.4 +/- 9 pg/ml), but there were differences between the different patient subgroups depending on the duration of the disease. The dose of insulin and the 1.25 D levels were linearly correlated (r = 0.3693, p = 0.0051). The patients with IDDM had normal 1.25 D levels. Exogenous insulin administration may have relevance for the interpretation of these results.

Adolescent↗