PubMed HealthSearch

Biomedical subjects

N P Gupta

Publications and source records attributed to N P Gupta.

At least 19 recordsLinked to original sources

Urinary bladder carcinoma as apparent cause of antepartum haemorrhage in pregnancy.

A 34-year-old multipara presented with painless profuse genital bleeding during the third trimester of pregnancy in a state of hemorrhagic shock. Haematuria because of urinary bladder carcinoma was found to be the cause of bleeding. Cystoscopy was useful for accurate diagnosis as well as for achieving haemostasis. This case emphasizes the possibility and importance of haematuria when dealing with a patient with antepartum haemorrhage.

Adenocarcinoma, Mucinous

Malignant pericystitis plastica.

A case of infiltrative bladder tumor presenting as diffuse perivesical and periureteral fibrosis is presented and termed malignant pericystitis plastica.

Aged

Rheumatoid factor: correlation with recurrence in transitional cell carcinoma of the bladder.

The serum rheumatoid factor was measured by the latex fixation test in different titrations in 100 cases of bladder tumors. The rheumatoid factor was found in transitional and squamous cell carcinoma of the bladder. The percentage of positive studies correlated well with the clinical staging of the tumors. The rheumatoid factor activity also correlated with the recurrence of transitional cell carcinoma. A high recurrence rate was found when the rheumatoid factor was present in contrast to a low recurrence rate when it was absent at the initial examination. The percentage of recurrences correlated with the titration of the rheumatoid factor. The mechanism of production of the rheumatoid factor and its correlation with tumor recurrence are discussed.

Carcinoma, Squamous Cell

Prevalence of Coxiella burnetii infection among humans and domestic animals of Rajasthan State, India.

A total number of 1806 sera comprising 1049 humans and 757 animals from four ecologically different areas of Rajasthan State were tested to determine the prevalence of complement-fixing (CF) antibodies to Coxiella burnetii (C burnett). Of the 1049 human and 757 animal sera tested, antibodies to C. burnetii were detected in 195 sera (18.6 per cent) and 187 sera (24.7 per cent), respectively. Among humans, the prevalence of infection with C. burnetii was highest in the desert area of Barmer district and the hilly area of Bundi district, viz 64.5 per cent and 28.2 per cent, respectively. It was slightly lower in the semi-arid and the arid zones of the State, viz Sirohi (20 per cent) and Jalore (13.7 per cent), whereas the irrigated areas of Kota and Jaipur had the lowest prevalence, 9.9 and 8.4 per cent, respectively. Among animals, the highest prevalence was detected in sheep (39.6 per cent), followed by cattle (29.9 per cent) and goats (18.6 per cent).

Animals

Rheumatoid factor in bladder tumors.

We used the standard latex fixation test to screen 71 patients with bladder tumors and appropriate controls for the rheumatoid factor. The rheumatoid factor was present in transitional and squamous cell carcinoma of the bladder. Positivity was correlated with staging and histological grading of the tumor. In control subjects it was present in squamous cell carcinoma of the penis and anal canal. The possibility of the circulating immune complex with tumor antigen and its antibody has been discussed.

Carcinoma, Squamous Cell

Sero-epidemiological survey of scrub typhus.

A total of 1017 human sera from ecologically different areas in the states of Rajasthan and Jammu & Kashmir were subjected to the CF test using the Gilliam strain antigen of R. tsutsugamushi. Results revealed that 2.4% and 3.5% of the populations examined in the two states respectively, were found to possess antibodies to the test antigen. The titres of positive sera varied from 1:8 to 1:32. Findings of this survey could be correlated with the local topography, presence or absence of vector and the exposure of susceptible population to the rickettsial agent. However, the presence of hidden foci in the neighbouring areas not covered by the current survey cannot be ruled out.

Antibodies, Bacterial