[Cardiomyopathies in the clinical practice].
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Adult↗
Biomedical subjects
N P Keĭzer
Publications and source records attributed to N P Keĭzer.
[Indicators of general insulin activity and free insulin of blood serum in myocardial infarct].
Data are presented on the base-line level of general insulin activity and free serum insulin determined by biological techniques in 45 patients during the acute and subacute phases of their myocardial infarction. Patients with normal body weight demonstrated a reduction of the insulin activity parameters during the initial days of the disease, the reduction being most distinct in a complicated course of the acute period. The indices of free insulin varied widely, and the mean values were close to the controls, although the majority of patients had a reduced level of free insulin in blood. During the subacute phase of myocardial infarction the indices of insulin activity and free insulin did not differ from the control figures in the majority of patients. The general insulin activity remained reduced during the subacute period as well if the course of the disease was complicated by the development of circulatory insufficiency. In obese patients the indices of insulin activity and free insulin exceeded during the acute period of myocardial infarction those of the control, and during the subacute stage of the disease they became even higher.
Acute Disease↗
[Carbohydrate tolerance in patients with myocardial infarct according to prednisolone-glucose tolerance test].
Sensitivity to carbohydrates was studied in 100 patients in the subacute period of myocardial infarction by the prednisolne-glucose tolerance test with parallel determination of the content of sugar and pyruvic and lactic acids. Latent, predominantly mild disorders of carbohydrate metabolism were revealed in most patients. Considerably diminished glucose tolerance (diabetic-type sugar curve) was encountered in 12.5% of patients with normal and in 17.9% of those with excessive body weight. The prednisolone-glucose tolerance test and the tests for the content of pyruvic and lactic acids conducted in dynamics showed a statistically reliable increase in the pyruvate level on a fasting stomach and after glucose loads and of the lactate level on a fasting stomach and at the end of the examination. In diabetictype glycemic curves, however, the peak sugar levels were paralleled by normal content of pyruvic and lactic acids. The glycemia indices revealed in dynamics of the prednisolone-glucose tolerance test were significantly higher in patients with an increased blood sugar content in the acute period of myocardial infarction.
Adult↗