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N P Lich

Publications and source records attributed to N P Lich.

7 recordsLinked to original sources
PubMed1979

[Dismutation as a metabolic pathway : transformation of the trimethyl 3,5,5, cyclohexanone (author's transl)].

Besides novel routes of biotransformation of xenobiotic substances recently reported, such as N-glucuronidation of teritary amines and quaternary ammonium componds, N-glucosylation, N-carbamylglucuronide formation from a primary amine, C-glucuronidation, conjugation with long-chain fatty acids, with polypeptides, carbon-chain elongation, stereospecific inversion of configuration at a satured carbon atom, formation of methylthio metabolites, the authors have described a new metabolic pathway: dismutation, in the case of 3,5,5, - trimethylcyclohexanone (dihydroisophorone). As a matter of fact, this compound leads, in vivo, to the formation of isophorone alpha and of cis and trans 3,5,5, - trimethyl cyclohexanols. These compounds, extracted from the urine of treated rats and rabbits, have been identified by gas-liquid chromatography and thin-layer chromatography.

Animals↗
PubMed1976

[Analysis of volatile N-nitrosamines. A brief review].

The different steps of analysis of volatile N-Nitrosamines: separation from product, clean up, detection, quantification and confirmation are reviewed and discussed. The two best analysis procedures are: 1) combined gas-chromatography; mass-spectrometry, 2) combined gas-chromatography; thermal energy analyzer. However a bundle of proofs is always necessary to ascertain the presence of Nitrosamines.

Chemical Phenomena↗