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N P Murray

Publications and source records attributed to N P Murray.

2 recordsLinked to original sources

Event-related potential evidence for the processing efficiency theory.

The purpose of this study was to examine the central tenets of the processing efficiency theory using psychophysiological measures of attention and effort. Twenty-eight participants were divided equally into either a high or low trait anxiety group. They were then required to perform a simulated driving task while responding to one of four target light-emitting diodes. Cortical activity and dual task performance were recorded under two conditions -- baseline and competition -- with cognitive anxiety being elevated in the competitive session by an instructional set. Although driving speed was similar across sessions, a reduction in P3 amplitude to cue onset in the light detection task occurred for both groups during the competitive session, suggesting a reduction in processing efficiency as participants became more state anxious. Our findings provide more comprehensive and mechanistic evidence for processing efficiency theory, and confirm that increases in cognitive anxiety can result in a reduction of processing efficiency with little change in performance effectiveness.

Anxiety↗

Gynaecomastia and heart failure--adverse drug reaction or disease process?

The presence of gynaecomastia was assessed in 444 male patients in order to determine the overall incidence of this condition. In addition, patients were assessed for liver function, age, weight, height and drug therapy, in an attempt to identify causative factors for the presence of gynaecomastia. The results indicate that there is a positive correlation between gynaecomastia and right and/or left cardiac failure. In addition, drug therapy with frusemide, amiloride and captopril was significantly correlated with an increased incidence of gynaecomastia in the study population; however this correlation was not present for either age or body weight index. These drugs are commonly used in the therapy of heart failure. This study highlights the difficulty of differentiating between whether or not pathology or drug therapy is the main contributing factor to a proposed adverse drug reaction.

Adolescent↗