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Biomedical subjects

N P Popov

Publications and source records attributed to N P Popov.

12 recordsLinked to original sources
PubMed1983

Vascular changes in hyperacute meningococcal sepsis as a manifestation of pathogenic action of immune complexes.

The analysis of post mortem examinations of 175 cases of meningococcal sepsis concentrates on a description of vascular changes as the chief manifestation of the given disease. The changes consisted in the destruction of the endothelium, mucoid swelling or fibrinoid changes of the wall of minute vessels, and disseminated intravascular blood clotting. In sum, these changes can be described as generalized microangiothrombopathy. In the affected vascular walls and in the thrombotic masses the presence of antigen-antibody immune complexes was found. It is therefore possible to regard hyperacute meningococcal sepsis as a manifestation of pathogenic action of immune complexes--as a consequence of massive blood invasion by antigen and of rapid formation of a great number of antigen-antibody complexes.

Adolescent↗
PubMed1983

[Computer input of graphic and alphanumeric information during radiation therapy dosage planning using the PAUK (semi-automatic coding) device].

A system of the input of initial information on a patient into the ES-1022 computer in the on-line mode for dosimetric irradiation planning has been tested. A semi-automatic coding device (SACD) has been utilized. The system can operate in two modes: on-line calculation of dose distributions and irradiation conditions; archivization of input initial data.

Online Systems↗
PubMed1975

[Vascular and immunological processes in the pathogenesis of meningococcal infection].

A pathomorphological investigation of 115 lethal cases of various forms of meningococcal infection was carried out. Meningococcemia, its instantaneous forms in particular, are characterized by acute decompensation of the lymphoid system and generalized microangiopathy with the thrombohaemorrhagic syndrome. Haemorrhagic necrosis of the adrenals and damage of the hypophysis represented manifestations of the acute decompensation of the hormonal regulation. Inflammatory changes in meningococcemia were observed not in all the cases (they were absent in 1/4 of the deceased). In meningitis (meningoencephalitis) without sepsis no generalized angiopathy was noted, immunomorphological changes were of a proliferative character. Previous sensibilization of the macroorganism was an important prerequisite for the development of meningococcal infection.

Acute Disease↗
PubMedDate not supplied

[Apparatus for cardiosynchronized artificial circulation].

The development of outfits for ancillary circulation is oriented towards improvement and construction of new pneumatic, hydraulic and electromechanical actuating systems--units intended for an optimal disposition of pressure waves moving from the pump to the aorta, etc. An inference is drawn about advantages and perspectives offered by functionally monitored actuating units, as well as about the need for the pulsating stream to pass through the low-power side intended to pre-set the shape of the pressure curve.

Austria↗