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Biomedical subjects

N P Shabalov

Publications and source records attributed to N P Shabalov.

At least 19 recordsLinked to original sources

Species, population and age diversity in cell resistance to adhesion of Neisseria meningitidis serogroups A, B and C.

The variation of cell adherence of meningococci serogroups A, B and C and influenza viruses was investigated in 11 animal species and in humans of different age groups (1st, 2nd, 3rd and 4th weeks; 2nd-3rd months; 4th-12th months, 2nd-3rd years; and 18th-60th years of life) as well as in women during pregnancy (17th-36th weeks) and childbirth. Red blood cells of all animals tested as well as of human newborns were absolutely resistant to attachment of meningococci. In neonatal and the later periods the human cells become far differently sensitive individually to meningococcal adhesion. In contrast, the viral adhesion was characterized by different individual cell sensitivity in all age groups tested. Pregnancy and childbirth did not influence the women's cell sensitivity to adhesion of Neisseria meningitidis. Different receptors are involved in interactions of human cells with influenza viruses and meningococci. The function of meningococcal receptors on human cells develops during postnatal ontogenesis. The variations express both specific (genetic) and ontogenetic (individual) differences in natural resistance to meningococcal infection.

Adolescent↗

[The action of bilirubin in vitro on the antioxidant activity and lipid peroxidation of the plasma and erythrocytes of cord blood].

Plasma and erythrocytes of cord blood were incubated with bilirubin (40-400 mkMol/l) for 30 min. This incubation resulted in reduction of lipid peroxidation both in plasma and erythrocytes. The antioxidant activity increased in erythrocytes after incubation, but decreased in plasma. It concluded that high concentration of protein-bound bilirubin and about its effect exerted an antioxidant effect and could influence the stability of blood cells.

Antioxidants↗

[Intrauterine infections: frequency and diagnosis].

Intrauterine infections occupy a considerable place in human pathology--a conclusion drawn on the basis of original and literature data. Herpetic, cytomegalic, mycoplasma and chlamydial infections are the most important among them. Intrauterine infections may be the cause of some diseases considered as somatic ones. The possibility of the pathology diagnosis of these disease not only on the basis of laboratory data but on the basis of characteristic structural changes of cells and tissues is shown.

Chlamydia Infections↗