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N Pasini

Publications and source records attributed to N Pasini.

15 recordsLinked to original sources
PubMed2000

Solidarity and the role of the state in Italian health care.

The article deals with the issue of solidarity in health care, with particular reference to the Italian context. It presents the difficulties of the Italian NHS and assesses the current proposal to counter the crisis of the Welfare State by giving up institutional arrangements, in order to favour the so-called 'social private'. Moreover, it addresses the question of prioritization and targeting in the context of health care, arguing for the insufficiency of the standard approach of neutral liberalism, and showing how the concept of solidarity might help to develop a different account. Lastly, it discusses the case of organ transplantation in Italy, as an example of solidarity-inspired health care policy.

Civil Rights↗
PubMedDate not supplied

Attenuation of influenza A/New Jersey/76 virus strain, preparation of live vaccine and vaccine reactogenicity in volunteers.

The NIB-3 strain (a recombinant of influenza A/New Jersey/76 and X-31 strains) was further attenuated by nine egg passages at 28 degrees C for the purpose of obtaining a "cold-adapted variant" suitable for preparation of live freeze-dried vaccine with 5% peptone. The vaccine with two infectivity titres, of 7 and 6 log EID50/dose respectively, administered intranasally, was studied in a double-blind placebo-controlled field trial. The reactogenicity of the vaccine was evaluated on the basis of fever reactions during the first three days after vaccination and by the detection of local virus recovery from throat swabs taken on the first four days after vaccination. The majority of vaccines had no fever. On the first day following vaccination the proportions of persons with low-grade fever (up to 37.4 degrees C) were the same in the groups given placebo and vaccine with 6 log EID50/dose respectively. In the group vaccinated with 7 log EID50/dose there were 8% more persons with low-grade fever than in the group given placebo, but this difference was not significant (P greater than 0.05). On the second and the third day after vaccination there was no difference between the proportions of persons with low-grade fever in all the three groups. The highest number of virus isolations, i.e. 26%, was found in persons vaccinated with 7 log EID50/dose, 72 h after vaccination. In the placebo group the virus was not isolated from any person during the entire course of the study.

Adaptation, Physiological↗
PubMedDate not supplied

HI antibody response in volunteers vaccinated with live influenza A/New Jersey/76 vaccine.

Live freeze-dried influenza A/New Jersey/76 vaccine prepared from the "cold-adapted variant" of NIB-3 strain. Three groups of about 50 persons were included in a double-blind placebo-controlled field trial. One group received the vaccine with 7 log EID50/dose, the other 6 log EID50/dose and the third received placebo. One half of persons from each group were given a second dose of the corresponding preparation after two weeks. The immunogenicity of the vaccine was evaluated by the determination of HI antibody conversion rate in seronegative persons. The proportion of vacinated persons with seroconversion, regardless of the number of doses, increased with time, and 16 weeks after vaccination reached the maximum value of 0.87 in persons given vaccine with 7 log EID50 per dose and 0.55 in those given 6 log EID50/dose. In twice-vaccinated persons the proportion of seroconversion was higher regardless of the virus titre of the vaccine. The highest proportion of seroconversion (0.93) was recorded in persons vaccinated twice with 7 log EID50/dose 16 weeks after vaccination.

Adaptation, Physiological↗
PubMedDate not supplied

[A simple lesion-free drop of the chorio-allantoic membrane of the chick embryo (author's transl)].

In the embryonated 4-5 days old chicken egg incubated in the normal vertical position, only the blunt top end, a small part of the egg surface, is covered by the embryo. Soon after rotation of the egg to the reverted vertical position with the blunt end down, the egg shell is pierced and the artificial air space is formed on the pointed end which is far from the region occupied by the embryo. Thus any possibility of lesion is avoided.

Allantois↗