[Clinical, biochemical and pathological-anatomical study of 3 patients with Weber-Christian disease].
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Biomedical subjects
Publications and source records attributed to N Popovici.
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The patients entering this study were divided into 3 series according to the administered drug treatment, being then followed up for at least 28 days for the main symptoms (pain, tumefaction, vasomotor disturbances, limited movements). The more satisfactory results were obtained in the patients receiving prednisone, indomethacin, propranolol, sympatholytics, vasodilators, calcium anabolisants, tranquilizers to which, at the right time, massage and kinesitherapy were associated.
A number of 50 patients admitted with arthritis and Reiter syndrome were investigated to detect the presence of Yersinia specific antibodies. The specific antibodies were evidenced in 5 patients (10%)--3 with antibodies to Y. enterocolitica and 2 with antibodies to Y. pseudotuberculosis, in titers greater than or equal to 1/160. The patients were followed in dynamics up to 3-4 months. The antibodies to Y. enterocolitica persisted in time longer than those to Y. pseudotuberculosis. For a better knowledge concerning the germs responsible for sero-negative arthritis, serological investigations for Yersinia, in the patients with arthritis, appeared as necessary.
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