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Biomedical subjects

N R Brewer

Publications and source records attributed to N R Brewer.

14 recordsLinked to original sources

Mammalian thermoregulation: species differences.

An understanding of the variation between species is a basic requirement if one is to give proper care to laboratory animals, select an appropriate animal to find answers to a specific question, and/or appreciate the limits in interpreting experimental results as they may apply to humans.

Animals↗

Comparative metabolism of copper.

Copper is required in trace amounts for many body functions. The prominent effects of Cu deficiency or Cu toxicosis differs greatly between animal species. Along with iron, Cu is necessary for the transfer of O2 via a cascade of enzymes so that energy may be available for vital body functions without overheating of the tissues through rapid oxidation. As a part of lysyl oxidase, Cu has an obligate function in the maturation of all connective tissue (including elastic tissue and bone) maintaining the form and integrity of all body organs. As a constituent of tyrosinase, Cu is involved in the formation of melanin, thus preventing albinism. Copper also is involved in the myelination of nerve fibers and the production of neutrophils, enkephalins, lipoproteins, and cholesterol. Copper must be properly sequestered to prevent toxicosis. Copper is stored primarily as metallothioneins and as superoxide dismutase and is transported primarily as ceruloplasmin or as low molecular weight proteins, peptides, and amino acids.

Animals↗

Nutrition of the cat.

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Animal Nutritional Physiological Phenomena↗