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Biomedical subjects

N R Olson

Publications and source records attributed to N R Olson.

At least 19 recordsLinked to original sources

Skin grafting of the larynx.

Skin grafting as a method of restoring the lumen in cases of laryngeal stenosis has been promoted and practiced in the past. Lately, little has been heard of the method. I have personally used skin grafting in almost every case of repair of acute injury or chronic stenosis of the larynx in the last several years. The rationale for grafting is (1) to cover any areas of epithelial loss or dehiscence during the healing period, (2) to reduce the chance of prolonged granulation and subsequent contracture, and (3) to serve as a logical material to use as the interface between a stent and the lumen of the larynx. This report discusses the use of skin grafting in 20 cases of severe acute injury or chronic stenosis. Other procedures needed to enhance the stenotic lumen are also described. In this series, 17 patients are decannulated, one wears a plug continually, and two did not or could not complete the recommended therapy. Among those completing therapy, 100% are either decannulated or wear a plug.

Adolescent

Laryngopharyngeal manifestations of gastroesophageal reflux disease.

Gastroesophageal reflux disease (GERD) contributes to the development of many otolaryngologic symptoms and conditions, including chronic throat clearing, cough, sore throat, contact ulcer and granuloma, globus pharyngeus, cervical dysphagia, cancer of the larynx, subglottic stenosis, and cricoarytenoid arthritis. These conditions are discussed and the pathogenesis of GERD is also detailed.

Deglutition Disorders

Nonclosure of pharyngeal muscle after laryngectomy.

A prospective study was carried out to evaluate a new technique of pharyngeal repair following laryngectomy. The purpose of this study was to see whether satisfactory healing would occur if the pharyngeal constrictors were not sutured across the closure in the pharynx. If healing proved to be satisfactory the procedure might eliminate the need for primary or secondary myotomy or pharyngeal plexus neurectomy to facilitate tracheoesophageal speech. The results indicate that healing is as good in the group who did not have muscle closure as in those who did.

Evaluation Studies as Topic

The problem of gastroesophageal reflux.

Gastroesophageal reflux is the "postnasal drip" of the 1980s. A large variety of symptoms result from reflux: some are merely nuisances, some are life threatening. This review covers those symptoms and diseases due to acid reflux that are of importance to the otolaryngologist.

Adult

Ototoxic effect of erythromycin therapy.

Thirty-two cases of sudden, symmetrical, high-frequency, sensorineural hearing loss associated with intravenous (IV) and oral erythromycin therapy have been published since 1973. We treated a patient with reversible ototoxicity associated with IV erythromycin for the treatment of legionnaire's disease.

Audiometry

Nontuberculous mycobacterial infections of the face and neck--practical considerations.

Cervicofacial nontuberculous mycobacterial (NTM) infections are a diagnostic and therapeutic dilemma which may be encountered by the Otolaryngologist. A review of the world's literature indicates that these infections are being diagnosed more frequently and that they far outnumber cervical infections by Mycobacterium tuberculosis. The organisms are ubiquitous. The portal of entry may be through a small defect in the skin or mucosa. They rarely, if ever, cause serious systemic illness. Diagnosis is by culture of the organism, however, cultures are usually not available at the time the patient is treated. Treatment, then, must be based on the results of skin tests, examination of pus and tissue, a "typical clinical presentation," and elimination of other diseases. The differential diagnosis is extensive. This review reports 21 patients with proven or suspected NTM infections of the face and neck. Eight of these patients were treated by traditional methods utilizing completed excision and, in some cases, drug therapy. Eleven were treated by curettage alone, and two more by curettage and drugs. The results were excellent by all of these forms of treatment. These findings support the proposition that curettage is a simple, safe, and effective method of treatmenting cervicofacial NTM infections and should be utilized as the primary treatment in all suspected or proven cases of this disease. The method dose not exclude other forms of treatment being utilized if they should be required.

Anti-Bacterial Agents

The omocervical flap.

The omocervical flap is recommended for replacement of neck skin involved with malignancy or radioecrosis, carotid artery protection, or closure of pharyngostomes. The flap is very strong and reliable. It has a permanent pedicle and can be turned without delay. It will reach beyond the midline. By using appropriate lateral positioning of the patient, neck surgery and flap transfer can be accomplished with minimum difficulty. This flap is recommended as an excellent functional and cosmetic flap for neck reconstruction.

Head and Neck Neoplasms

The surgical anatomy of the spinal accessory nerve and the internal branch of the superior laryngeal nerve.

Injury to the spinal accessory nerve may occur during conservation neck dissection. In supraglottic laryngectomy preservation of the internal branch of the superior laryngeal nerve has largely been ignored. Cadaver dissection and diagrams are used to review the surgical anatomy of these two structures. Particularly important are the relationship of the spinal accessory nerve to the sternocleidomastoid muscle, its interaction with the cervical plexus, and its superficial path inferiorly. Landmarks for the identification of the internal branch of the superior laryngeal nerve are indicated, and technique for preservation is described. An intact accessory nerve can be efficiently preserved thereby eliminating the shoulder syndrome. Significant sparing of the internal branch of the superior laryngeal nerve can be routinely accomplished as an aid in minimizing postoperative aspiration.

Accessory Nerve

Wound healing by primary intention in the larynx.

In this article, I have attempted to bring forward well known and widely accepted principles of wound healing and to show how they are pertinent to the repair of severe acute and chronic crush injuries of the larynx. The process has brought some time honored practices into question and forced a search for new, more effective ones.

Epithelium

Traumatic lesions of the salivary glands.

Injuries to the region of the major salivary glands, especially the parotid, may have important sequelae and require insight and persistence to manage. This is an area in which microsurgery comes into its own, especially for repair of the duct or nerve. In cases of severe injury or complications, the removal of the involved gland is always an option.

Cheek

Angiosarcoma of the maxillary sinus: report of case.

The third reported case of primary angiosarcoma of the paranasal sinuses is presented. The neoplasm occured in the left maxillary sinus of a 26-year-old white woman. The patient was treated with external irradiation with cobalt of a total dose of 7,000 rads. No evidence of recurrence has been reported.

Adult