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Biomedical subjects

N R Saeed

Publications and source records attributed to N R Saeed.

12 recordsLinked to original sources
PubMed2005

Oral cancer: delays in referral and diagnosis persist.

Oral cancer accounts for around 1% of all new cancers diagnosed in the United Kingdom every year. Mortality rates remain relatively high and prognosis is worst in cases of more advanced disease at time of diagnosis. Early identification of malignant lesions and speedy referral to a specialist for treatment are therefore important. The reasons and extent of the delays at the different stages between a patient first noticing an oral lesion and attending a health care professional and then being referred for specialist care have previously been studied and consistently found to be longer than desired. The National Oral Cancer Awareness Week (NOCAW), first run in 1995, aimed to increase the awareness of oral cancer amongst health care professionals and the public. It has since been repeated and is now an annual event. Alongside publications by the British Dental Association and guidelines circulated by the Department of Health on oral cancer diagnosis and referral, it is hoped this will lead to a decrease in the delay between the onset of oral cancer and patients receiving appropriate treatment. We looked at the previously published data on referral delay in oral cancer both in the United Kingdom and overseas and then identified delays in referral of oral cancer patients in a region that had been studied before NOCAW was introduced, to see if this was having any effect on referral delays. We found that despite the great publicity raised by NOCAW and the other publications and courses on oral cancer since the original audit, patient delay and referral delay have not improved. We conclude that more needs to be done to transfer guidelines to everyday practice.

Anniversaries and Special Events↗
PubMed2004

Reconstruction of the temporomandibular joint by the transfer of the free vascularised second metatarsal.

We present our experience of a series of patients who presented for salvage reconstruction of the temporomandibular joint (TMJ) for relief of pain. Reconstruction was achieved by transfer of the free vascularised second metatarsal. This technique has been used for a total of seven TMJ reconstructions in five patients. We describe the surgical anatomy, technique and results during the last 18 years. One joint failed but the other six surviving joints continue to provide adequate pain-free function. We advocate this technique for autogenous salvage reconstruction in joints that have been previously operated on unsuccessfully.

Adolescent↗
PubMed2004

Angina bullosa haemorrhagica presenting as acute upper airway obstruction.

We report a case of acute upper airway obstruction caused by a rapidly expanding blood-filled bulla in the oropharynx (angina bullosa haemorrhagica), requiring tracheal intubation. The larynx could not be visualized by either awake fibreoptic laryngoscopy or direct laryngoscopy under anaesthesia. Surgical tracheostomy was therefore performed under general anaesthesia.

Acute Disease↗
PubMed2003

Castleman's disease presenting as a midline neck mass.

We report the case of a 13-year-old girl who presented with a painless midline submental mass. Excision biopsy confirmed Castleman's disease of the hyaline-vascular type. This unusual condition needs to be considered in the differential diagnosis of masses arising in the neck.

Adolescent↗
PubMed2003

A retrospective study of the costochondral graft in TMJ reconstruction.

A retrospective review of 76 costochondral grafts (57 patients) was undertaken to determine outcome with respect to the extent of previous surgery (none, disc surgery or soft tissue graft, alloplastic disc, alloplastic joint, previous graft) and to initial and preoperative diagnosis. The minimum follow up period was 2 years and for each patient both subjective (pain and dietary interference scores) and objective (interincisal distance) data was recorded. Collectively there was improvement in pain (mean 6.7 to 3.5) and diet (mean 2.2 to 3.0) scores with a moderate increase in interincisal distance (mean 21 to 24mm). In patients with no previous surgery, arthritic disease or congenital deformity the costochondral graft performed well but in patients with previous alloplastic discs and/or total joints the results were less predictable. A preoperative diagnosis of ankylosis was associated with a high complication and further surgery rate suggesting caution in this group of patients.

Adolescent↗
PubMed2001

Internal derangement of the temporomandibular joint treated by discectomy and hemi-arthroplasty with a Christensen fossa-eminence prosthesis.

Patients with internal derangement of the temporomandibular joint (TMJ) who have failed to respond to conservative treatment can be treated by discectomy and insertion of a Christensen fossa-eminence prosthesis, provided there is no clinical or radiological evidence of condylar disease (such as avascular necrosis). A total of 42 patients who had significant symptoms related to internal derangement of the TMJ, despite nonsurgical treatment, had discectomies and fossa-eminence prostheses inserted. Preoperative and postoperative measurements were recorded for Gape, Pain and restriction of feeding. All but one of the 34 patients showed improvements in their symptoms postoperatively. There were no serious postoperative complications.

Adolescent↗
PubMed2001

Temporomandibular joint replacement in rheumatoid-induced disease.

We report a series of seven patients with rheumatoid arthritis whose temporomandibular joints were replaced using the Christensen joint system. Patients were assessed before and after operation both subjectively (pain and dietary interference) and objectively (interincisal distance). Patient's satisfaction with the outcome of operation was also recorded. All patients showed improved visual analogue scores for pain and dietary interference after their operations and an improvement in interincisal distance was recorded in five of the patients (the remaining two having had the operation for anterior open bite). Overall satisfaction was high and no patient has rejected the prosthesis or had any substantial complications. The mean follow up period is 30 months (range 8-50). We suggest that patients with severe, rheumatoid-induced temporomandibular disease should be considered for arthroplasty as it is possible to restore some normal function and appearance.

Adult↗
PubMed1993

The oral surgery/orthodontic interface: 2. Local causes of malocclusion.

This is the second of two articles discussing the minor oral surgery/orthodontic interface. The vital role played by the general dental practitioner in monitoring the normal development of the occlusion and the early diagnosis of the local causes of malocclusion was emphasized in the first article. Part 2 discusses the problems associated with the prominent labial frenum, supernumerary teeth and submerged deciduous molars.

Humans↗
PubMed1993

The oral surgery/orthodontic interface: 1. Ectopically positioned teeth.

The number of patients seeking orthodontic treatment has increased over the last decade. A proportion of these patients present with minor irregularities due to the so-called 'local causes' of malocclusion, many of which require surgical treatment. Some general dental practitioners have taken up the challenge of correcting these causes and the resulting malocclusion themselves; however, all practitioners must be aware of the treatment options available and the surgical and orthodontic considerations to be taken into account. This will allow informed discussion with patients. In this, the first of two papers, the management of ectopically positioned teeth is discussed.

Cuspid↗