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N R Tiras

Publications and source records attributed to N R Tiras.

28 records · Page 2Linked to original sources
PubMed1988

[Synapses with a different synaptic contact structure in the cerebellar cortex].

The ultrastructure of cerebellar axosomatic (inhibitory) and axo-dendritic (excitatory) synapses were studied on the Purkinje cells and in the lower molecular layer of guinea-pigs and rats, respectively. It was shown that synaptic contacts of excitatory and inhibitory synapses differed in the existence of desmosome-like structures near the active zones. The classification of synaptic functions according to the ultrastructure of specialized contacts, earlier developed to identify neurons of lower vertebrates, is supposed to be applicable to the nervous system of higher vertebrates.

Animals↗
PubMed1987

[Differences in the cytoskeleton in inhibitory and excitatory synapses].

The cytoskeleton of afferent chemical synapses, with various ultrastructure of contact zones, was examined in the Mauthner cells of the goldfish. The synapses with combined active zones and desmosome-like specialized contacts possessed a well developed cytoskeleton consisting of filaments and microtubules oriented towards the synaptic apposition. Regular arrays of synaptic vesicles oriented in the same direction were observed beyond and near the active zones. The cytoskeleton of the synapses lacking desmosome-like formations was diffusely organized throughout the boutons. The distribution of vesicles in the vicinity of active zones was also not ordered. The role of cytoskeleton in organization of the two morphologically distinct synapses is discussed. A special function of cytoskeleton as an intermediary between synaptoplasm and membrane is regarded as a necessary basis for plasticity of excitatory rather than inhibitory synapses.

Animals↗