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Biomedical subjects

N Reame

Publications and source records attributed to N Reame.

10 recordsLinked to original sources
PubMed2000

Relation of demographic and lifestyle factors to symptoms in a multi-racial/ethnic population of women 40-55 years of age.

A community-based survey was conducted during 1995-1997 of factors related to menopausal and other symptoms in a multi-racial/ethnic sample of 16,065 women aged 40-55 years. Each of seven sites comprising the Study of Women's Health across the Nation (SWAN) surveyed one of four minority populations and a Caucasian population. The largest adjusted prevalence odds ratios for all symptoms, particularly hot flashes or night sweats (odds ratios = 2.06-4.32), were for women who were peri- or postmenopausal. Most symptoms were reported least frequently by Japanese and Chinese (odds ratios = 0.47-0.67 compared with Caucasian) women. African-American women reported vasomotor symptoms and vaginal dryness more (odds ratios = 1.17-1.63) but urine leakage and difficulty sleeping less (odds ratios = 0.64-0.72) than Caucasians. Hispanic women reported urine leakage, vaginal dryness, heart pounding, and forgetfulness more (odds ratios = 1.22-1.85). Hot flashes or night sweats, urine leakage, and stiffness or soreness were associated with a high body mass index (odds ratios = 1.15-2.18 for women with a body mass index > or =27 vs. 19-26.9 kg/m2). Most symptoms were reported most frequently among women who had difficulty paying for basics (odds ratios = 1.15-2.05), who smoked (odds ratios = 1.21-1.78), and who rated themselves less physically active than other women their age (odds ratios = 1.24-2.33). These results suggest that lifestyle, menstrual status, race/ethnicity, and socioeconomic status affect symptoms in this age group.

Adult↗
PubMed1991

Symptom patterns in women with premenstrual syndrome complaints: a prospective assessment using a marker for ovulation and screening criteria for adequate ovarian function.

This study examined the symtom patterns of women seeking help for Premenstrual Syndrome (PMS) complaints. Seven women who were less than 35 yrs, within 10% of ideal body weight and who had experienced a full-term pregnancy, completed a daily health diary during an ovulatory menstrual cycle. In the luteal phase, symptom summary scores of the PMS group increased (P less than 0.05) and were markedly higher (P less than 0.5) from baseline acyclic scores of four ovulatory women who denied menstrual-related distress. To examine severity changes in individual symptoms, a total of 399 cases representing 57 symptoms from the seven 45-day diaries were evaluated for menstrual cycle entrainment. Of the 246 symptoms that met the criteria for a cycle phase change (62%), the classic PMS pattern of low/high severity was the most common (40%). Seven different subtypes of the PMS pattern were identified; four of these subtypes demonstrated a severity score elevation at ovulation as well as during the premenstruum. For individual women, the majority of symptoms (65%) displayed only two pattern types, suggesting a common rhythmic entrainment of symptom intensity.

Adult↗
PubMed1984

Pulsatile gonadotropin secretion during the human menstrual cycle: evidence for altered frequency of gonadotropin-releasing hormone secretion.

Pulsatile secretion of LH and FSH was examined to determine if the frequency of LH pulses, and by inference pulsatile GnRH secretion, varied during the human menstrual cycle. Blood samples were obtained at 10- or 20-min intervals for 12 or 24 h at 7-day intervals during the same ovulatory cycle in eight normal women. Ovarian steroids showed the expected cyclical changes and mean plasma FSH concentrations showed an inverse relationship to estradiol, being low when estradiol was greater than 150 pg/ml. Sampling every 10 min revealed a constant LH pulse amplitude but LH pulse frequency increased (from 11.8 to 14.3 pulses/12 h) during the follicular phase. LH pulse frequency was not further increased in two women sampled during the LH surge, but pulse amplitude was markedly higher. During the luteal phase LH pulse frequency was reduced to eight pulses/12 h but frequency was more variable between subjects than in the follicular phase. LH pulse amplitude showed striking variation (0.8-29.4 mIU/ml) during the luteal phase of the cycle and large LH secretory episodes which lasted 1-3 h were irregularly interspersed among periods of low amplitude LH secretion. These data show that the frequency of LH pulses, and by inference GnRH secretion, varies during the menstrual cycle but the degree of change is less than reported in previous studies. This observation may explain the reported efficacy of fixed frequency GnRH regimes in inducing ovulation and cyclical ovarian function.

Adult↗
PubMedDate not supplied

Informed consent issues in assisted reproduction.

Given the enormous ethicolegal controversies surrounding the use of assisted reproductive technologies (ART) in the United States, the most important role for nurses may be helping couples and third party participants obtain fully informed consent. The high compensation fees for egg donors may place them at special risk of exploitation. New government and professional guidelines, broader representation on ethics committees, and expanded counseling about risks and benefits can help reduce the potential for litigation and enhance patient autonomy.

Consumer Advocacy↗
PubMedDate not supplied

Menstrual Health products, practices, and problems.

This review article examines factors affecting normal variations in menstrual flow, methods used to estimate vaginal blood loss, menstrual health problems related to hygiene practices, and methods of assessing tampon absorbancy. Preliminary studies from this laboratory suggest that normal, cycling women exhibit menstrual flow rates that are significantly higher during the day than at night; also that menstrual blood has a more acid pH than previously reported, and that it demonstrates unique biological properties unlike peripheral venous blood. Women in wheelchairs may be at special risk for the development of menstrual health problems because of difficulties with hygiene management as evidenced by results of a study of 22 women with traumatic spinal cord injuries.

Blood Chemical Analysis↗