[Conservative surgery of malignant neoplasms of the renal parenchyma and of the upper excretory passages. Prognosis and therapy].
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Biomedical subjects
Publications and source records attributed to N Rizzello.
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Sixteen patients having undergone ureterosigmoidostomy have been examined using fiberoptic coloscopes. Morphology and function of both the colonic mucosa and the ureteral stumps have been evaluated by direct observation, biopsy brush cytology and i.v. injection of methylen blue. The obtained encouraging results point to this fiberendoscopic diagnostic approach as an easy and useful follow-up examination of patients with intestinal urinary diversions.
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The authors report the results of a retrospective study regarding 214 patients (mean age 73, smallest follow-up 6 months, greatest 70 months, average 42 months) affected by advanced prostatic cancer histologically demonstrated, observed from January 1983 to December 1990 and subject to hormonal treatment. They particular compared so-called "total androgenic suppression" (Gn-RH analogous or orchiectomy plus antiandrogen) with the "partial androgenic suppression" (Gn-RH analogous or orchiectomy). The authors report the results of the treatment regarding the subjective and the objective response, evaluated with NPCP criteria. Moreover the actuarial aspects of response and survival curves of two groups of patients are compared. The authors conclude that total compared to partial androgenic suppression does not offer significant advantages as regards to objective response and present their current treatment of advanced prostatic cancer.
The authors report results in 10 patients (5 with renal neoplasms in a single kidney, 4 with healthy contralateral kidney, and one with a pathological opposite kidney following conservative surgery: 4 surgical enucleations and 6 partial nephrectomies.
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