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N S Alekseeva

Publications and source records attributed to N S Alekseeva.

15 recordsLinked to original sources
PubMed2006

[The role of neurovisualization methods in diagnosis and verification of vertigo etiology].

Roentgen computed tomography (RCT) and MR-imaging (MRI) were used in investigation of vertigo etiology and affection of the cochleovestibular analyzer in 130 patients aged 28 to 74 years with recurrent systemic rotatory vertigo or its other symptoms. All the patients have undergone comprehensive otoneurological examination, RCT and MRI which showed that peripheral cochleovestibular syndromes (PCVS) caused by arterial hypertension (AH), atherosclerosis (AS), vascular dystonia (VD) are rarely characterized by focal alterations in the brain. PCVS comparison with blood flow in the vertebral arteries (VA) detected most frequently anomalies and asymmetries of the diameters. MR-angiography plays an important role in verification of pathology of intracranial VA. In central cochleovestibular syndrome (CCVS) with AH, AS, VD, principal pathological changes were registered in the brain trunk and cerebellum by MRI. Vestibulometry and otoneurological method detect not only vascular cochleovestibular peripheral and central syndromes but also to make differential diagnosis. RCT and MRI verify cochleovestibular syndromes in patients with multiple encephalomyelitis, VIII nerve neurinoma and tumors of the posterior cranial fossa.

Adult↗
PubMed2006

[Vertigo and peripheral ischemic cochleovestibular syndrome caused by circulatory insufficiency in the vertebrobasilar system].

We studied characteristics of vestibular and acoustic disorders in patients with arterial hypertension, atherosclerosis and vascular dystonia; correlation between peripheral cochleovestibular syndromes (PCVS) and circulation in the major and intracranial arteries, central hemodynamics, organic changes in the brain. We discovered that anomalies and asymmetry in vertebral arteries diameters, stenoses, reduced stroke and minute blood volumes play an essential role in development of PCVS. The latter are rarely accompanied with ischemic foci in the brain. Medication of vascular vertigo consists in administration of an adequate drug. We believe that betaserk is most effective.

Adult↗
PubMed2006

[Vestibular cochlear disturbances in multiple sclerosis].

To specify the character of vestibular cochlear disturbances in multiple sclerosis (MS) and mechanisms of their formation, the objective quantitative evaluation of experimental caloric nystagmus using the computer electronystagmographic method and a comparison of hearing impairment with asymmetry of vestibular reactions were conducted in 48 patients with MS. The peculiarities of vestibular disturbance found in the study suggest a predominance of central vestibular syndrome with both subtentorial and supratentorial traits. The influence of the heat stimulus of vestibular analyzer (hot water caloric test) in multiple sclerosis revealed during computer electronystagmography may have diagnostic value.

Adult↗
PubMed2005

[Epidemiology, clinical features and betaserc therapy of vertigo in initial and reversible cerebrovascular pathology].

The study comprised two sections: epidemiologic and clinical. The aim of the epidemiologic investigation was to determine prevalence of vertigo, including its mild cases, in patients with initial and reversible forms of cerebrovascular pathology. While screening an open population, 726 men and women aged 35-60 years have been examined using uniform program. Vertigo was detected in 30%, frequent and long-lasting one in 14.6% cases (8.1% men and 21.9% women, p < 0.001). A clinical section included a profound examination of 40 patients. Along with duplex scanning of major brain arteries, neurologic and otoneurologic examination of the patients, aucoustic stem evoked potentials have been registered. Marked dysfunctions of autonomic nervous system and changes in functioning of different vestibular analyzer regions were revealed. High efficacy of betaserk used during 2 months in dosage 16 mg three times a day was demonstrated by improvement of the patient's state in 97% cases.

Adult↗
PubMed2005

[Vertigo and a role of neurovisual methods in it etiology and diagnosis].

Investigation of vestibular system using a standard method of electro-nystagmography in complex otoneurologic examination does not provide enough information on the etiology of vestibular analyzer lesion, location and diffusion of the pathological process. Neurovisual methods, in particular MRI and CT, have demonstrated high diagnostic validity in such pathological states as tumors of pons cerebellum and posterior focca; infarctions in the stem and cerebellum regions. The study revealed a role of MRI and CT in etiology of vertigo and lesions of cochleovestibular analyzer. One hundred thirty patients aged 28-74 years with recurrent attacks of systemic rotary vertigo and other its appearances have been examined. In 14 (11%) patients such an attack was accompanied by loss of consciousness, falls, double-vision and other neurological symptoms. All the patients underwent otoneurological examination, computer electronystagmography, auditory evoked potentials registration, CT and MRI. It is shown that peripheral cochleovestibular syndromes caused by arterial hypertension, atherosclerosis and autonomic vascular dystonia are rarely characterized by focal cerebral changes (11 patients by CT data and 17 by MRI).

Adult↗
PubMed2004

[Cochleovestibular syndromes in vertebrobasilar insufficiency].

The study aimed at (1) identification of the main vestibulometric characteristics of peripheral cochleovestibular syndrome caused by arterial hypertension, atherosclerosis and vegetative vascular dysfunction, (2) elucidation of the pathogenic peculiarities of its formation and (3) evaluation of therapeutic efficacy of betaserc in peripheral vertigo. Eighty-five patients with peripheral cochleovestibular syndrome (PCVS) were studied. On the base of the data of ultrasonic examination of major cranial arteries, arterial blood pressure, central hemodynamics and structural cerebral changes, it is shown that abnormalities of vertebrobasilar system play an important role in PCVS development. Stenosis of spinal and internal carotid arteries was found in a limited number of cases. A conclusion is made on involvment of hemodynamic mechanism of blood circulation insufficiency in the inner ear at microcirculating level in ischemic PCVS pathogenesis. A study of the structural cerebral changes revealed that PCVS were not accompanied by the ischemic foci in the brain. Pharmacotherapy of peripheral vertigo of vascular etiology is based on the right choice of the drugs optimizing blood circulation in combination with vestibulolytics. Therapeutic efficacy of 2-month betaserc course in peripheral vertigo has been proved.

Adult↗
PubMed2000

[The status of cerebral hemodynamics in patients with vertebro-basilar insufficiency syndrome].

The state of venous and arterial cerebral hemodynamics was studied using ultrasonic dopplerography with application of hypo- and hypercapnia, angioencephaloscintigraphy with pertecnetate Tc-99m in 48 patients with syndrome of vertebrobasilar insufficiency. Estimation was performed in patients by the results of neurological and otoneurologic evidence, the data of nistagmography and registration of the truncal evoked potentials. It was found that at early stages of the development of vertebrobasilar insufficiency's syndrome disorders of vasomotor reactivity and disturbances in venous hemodynamics play a leading role in its pathogenesis. Stenosis damages of extra- and intracranial arteries become dominating in subsequent clinical picture.

Adult↗
PubMed1990

[Surgical treatment of chronic ischemic heart disease].

The authors suggest a new complex approach to the surgical treatment of ischemic heart disease. Operation of coronary shunting for the restoration of the coronary blood flow, operation of partial ileoshunting for correction of hyperlipoproteinemia, plexotomy for removal of the vasospastic component. The sequence of the operations may vary, each one can also be undertaken independently. The operations were conducted on 315 patients. The follow-up period is up to 8 years. Patency of the mammary-coronary shunts was 93.5%, of autologous veins shunt--65%. Disappearance of the signs of coronary spasm++ and stable normalization of the lipid spectrum are noted.

Adult↗