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N S Atalay

Publications and source records attributed to N S Atalay.

3 recordsLinked to original sources
PubMed1996

Is it possible to trigger collagen synthesis by electric current in skin wounds?

The effect of direct micro currents on collagen synthesis in wound healing on the 3rd day of wounding has been examined in rabbit skin. Two circular skin wounds were formed bilaterally on the gluteal region and current was applied to one of the wounds and the other was taken as the control with placebo electrode on it, the current intensities being 200 microA and 400 microA and application time 72 hrs with 8 hr/day. The hydroxyproline content was found to be increased in wound tissue at the end of 72 hrs of applying current which indicated that collagen synthesis is promoted by electric current.

Analysis of Variance↗
PubMed1996

Biochemical and structural approach to collagen synthesis under electric fields.

The effects of electric fields of different intensities and directions on the collagen synthesis of guinea pigs was studied. The effects of vertical and horizontal electric fields of 1.9 kV/m and 0.9 kV/m, generated with voltages of 300 V and 150 V DC, respectively, on collagen synthesis, was evaluated by assessing the amount of hydroxyproline in the liver tissue, and by histological examination of tissue samples. The Stegemann-Stalder method was used to determine hydroxyproline content of the tissues. While the 0.9 kV/m vertical and horizontal electric fields substantially decreased the amount of hydroxyproline in the liver, the 1.9 kV/m electric fields in both directions increased the hydroxyproline content. The vertical electric field was more effective than the horizontal one both in the increases and the decreases. These findings were verified histologically.

Animals↗