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Biomedical subjects

N S Painter

Publications and source records attributed to N S Painter.

At least 19 recordsLinked to original sources

Diverticular disease of the colon. The first of the Western diseases shown to be due to a deficiency of dietary fibre.

Diverticular disease of the colon is a new disease that appeared at the beginning of this century. It is now the commonest disease of the colon in the Western world, being found in 1 in 3 people of over 60 years of age. The pathogenesis of the disease involves excessive segmentation, but this does not explain its aetiology. The historical appearance of the disease on the clinical scene and its geographical distribution suggest that it is due to the removal of fibre from carbohydrates. The author treated 70 patients with symptomatic diverticular disease with a high-fibre diet. The results of this and the effects of bran are discussed.

Black or African American↗

Constipation.

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Colonic Diseases, Functional↗

Sterculia bulk-forming agent with smooth-muscle relaxant versus bran in diverticular disease.

Sterculia with and without a smooth-muscle relaxant (alverine citrate) had similar beneficial effects on constipation and reduced the transit times in diverticular disease. Intracolonic pressure, however, varied with the preparation used. Though both preparations relieved the symptoms of diverticular disease, the one containing alverine citrate was more effective. Part of the mode of action of bran may be to relax the smooth muscle of the gut, since its actions were more comparable to those of sterculia plus alverine citrate than to those of sterculia alone.

Clinical Trials as Topic↗

Brown bread.

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Bread↗