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Biomedical subjects

N S Petrov

Publications and source records attributed to N S Petrov.

At least 19 recordsLinked to original sources
PubMed1984

[Role of polypeptide factors of the hypothalamus and epiphysis in regulating the function of stem cell precursors of granulomonopoiesis].

The claster- and colony-formation capacity of the offls--precursors of granulomonopoiesis in 29 normal subjects was studied in a bilayer agar system. Parallel cultures were used to investigate the effects of polypeptide factors of the hypothalamus and epiphysis. It was found that polypeptide factors of the hypothalamus and epiphysis have a regulatory influence on granulomonopoiesis at the level of precursor cells.

Animals↗
PubMed1982

[Colony-forming capacity of precursor cells of granulomonopoiesis in the liver and spleen at different stages of human embryo- and fetogenesis].

The claster- and colony-forming capacities (CFF) of cells-precursors of granulomonopoiesis (CPGM) in the livers and spleens of 37 human embryos and 9 foetuses were studied in the agar system. The CFC of CPGM in the liver and spleen of 6-8 week old embryos were higher than those during the later embryogenesis. In haemopoietic cell suspension, separated from liver cells, the CFC of CPGM were lower than in the total cell suspension from the liver of 6-8 week old embryos to constant within 6-16 weeks of embryogenesis. The discussion involves stem cell heterogeneity in human embryogenesis, a possible role of the embryonal liver in regulating the number of granulopoietic cells-precursors and their functional activity.

Clone Cells↗
PubMed1977

[Several indices of the functional state of the pituitary--adrenal cortex system in chronic alcoholism].

The adrenal cortex functional activity in males with alcoholsim of the 2nd stage (128 cases) in respect to the production of glucocorticoids and mineral-corticoids is decreased. The biosynthesis of androgens, as can be seen by the 17-KS urine excretion, is increased. Abstinence from alcohol during treatment with teturam in combination with neuroleptical drugs was accompanied by an increased elimination of glucocorticoids and a normalization of the metabolic indices of the main electrolytes. In all the examined cases of alcoholism with the 2nd stage irrespective of the duration of the disease there was an increased amount of androgens, possibly as a compensatory reaction to metabolic disturbances, due to chronic alcoholic intoxication.

17-Hydroxycorticosteroids↗