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Biomedical subjects

N S Sankar

Publications and source records attributed to N S Sankar.

7 recordsLinked to original sources

Health information on the Web: pregnancy.

The internet and computers have already become an important part of the daily lives of many. Through the touch of a button we can now obtain almost any information we desire without even leaving our homes. Although pregnancy is a common physiological event, anxiety is one of its frequent accompaniments and the anxiety may be of a high degree. Every woman desires to know in great detail about her own pregnancy. Even though the web is so easily accessible it is, nevertheless helpful to know which websites to surf in order to avoid wasting valuable time. The following list is a compilation of such sites, all of which have been tested and proved to be both valuable and informative; they should, moreover, provide interesting reading.

Female↗

Extramedullary plasmacytoma presenting as upper back pain.

Extramedullary plasmacytoma (EMP) is a rare soft tissue plasma cell tumour, usually presenting as a mass within the upper respiratory tract. It is most unusual for it to present in the posterior mediastinum as a primary solitary lesion. Discussed here is the case report of a patient who initially presented with musculoskeletal pain. Subsequent investigations, however, revealed the cause to be an EMP; diagnosis was made on finding aggregates of plasma cells on histological examination of the tissue specimen. The latter had been obtained by way of a computerised tomography scan guided biopsy of the tumour. Bone marrow aspiration studies showed no evidence of multiple myelomatosis. There was significant clinical improvement in response to radiotherapy. It is possible that this might represent one of the first documented reports of a primary solitary EMP in the posterior mediastinum.

Back Pain↗

Pulled elbow.

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Algorithms↗

Lessons to be learned: a case study approach: metastatic bronchogenic carcinoma presenting as a gluteal abscess.

It is well known that bronchogenic carcinoma frequently metastasises to the bony skeleton, but it is most unusual for it to present in the form of a musculoskeletal abscess. Presented here is the case report of a patient with what appeared initially to be a right sided gluteal abscess and which turned out to be the metastasis from a bronchogenic carcinoma. The Magnetic Resonance Image (MRI) scan carried out proved to be very helpful in arriving at a probable clinical diagnosis; however, it was histopathological studies of the abscess wall itself that ultimately gave the definitive diagnosis. We believe that this may represent one of the first documented cases in which on MRI scan has been used to confirm the presence of a gluteal abscess.

Abscess↗

Lessons to be learned: a case study approach diuretic therapy and a laxative causing electrolyte and water imbalance, loss of attention, a fall and subsequent fractures of the tibia and fibula in an elderly lady.

The case is described of a hitherto well, alert and intelligent lady of 85 years of age, who commenced medication with diuretics--prescribed for mild congestive cardiac failure; she developed constipation consequent upon the diuresis and dehydration thereby provoked. As a result she began to take, unknown to her general practitioner, regular and increasing amounts of laxatives. At about this time she was noted by her son to become "rapidly senile"--with the result that she fell on account of losing her normally good concentration and attention; she sustained fractures of the right tibia and fibula. Shortly after admission to hospital she was premedicated, anaesthetised and operated upon, following which there was a postoperative regimen comprising several litres of low sodium isotonic infusions, all given intravenously. She was found at this point to be severely hyponatraemic with a low serum osmolality, but following the institution of water restriction rapidly improved as her serum sodium rose again; there was an accompanying massive diuresis as the previously retained water was voided. Concomitant with the serum sodium rise her mental concentration and attention regained their former levels. The biochemical and cellular mechanisms underlying this patient's symptoms are discussed.

Accidental Falls↗

Lessons to be learned: a case study approach. Finger discoloration due to silver nitrate exposure: review of uses and toxicity of silver in clinical practice.

A 29 year-old lady attended the Accident and Emergency Department of a District General Hospital complaining of increasing black discoloration of the tip of her left middle finger; the appearance resembled that of gangrene. However, it was established that she had been applying silver nitrate to her finger, as prescribed by her general practitioner for the treatment of a small granuloma. Hence, the true diagnosis was of localised tissue necrosis, secondary to application of the silver nitrate sticks. On early discontinuation of the therapy, there was complete recovery. In consequence, it is recommended that the practice of unsupervised local application of silver nitrate to the fingers should be discontinued. Opportunity is taken herein to review the uses of silver nitrate in clinical situations--and of silver in any of its many other forms--together with their respective adverse effects.

Adult↗