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N Sahin

Publications and source records attributed to N Sahin.

45 records · Page 3Linked to original sources

Exploring the sociotropy-autonomy dimensions in a sample of Turkish psychiatric inpatients.

The present study explored the constructs of sociotropy and autonomy with a group of Turkish depressed inpatients, who were administered the Beck Depression Inventory, the Dysfunctional Attitudes Scale, the Automatic Thoughts Questionnaire, and the Sociotropy-Autonomy Scale. A comparison group of students from three SES levels also were included in the study. Comparisons were made on the scale scores among the non-dysphoric students, the dysphoric students, and the depressed patients. The results seem to support the relationship of sociotropy with other depression measures in both samples. However, several problems were encountered with the construct autonomy as it is conceptualized in the Sociotropy-Autonomy Scale.

Adolescent↗

Reliability and validity of the Turkish version of the Automatic Thoughts Questionnaire.

The present study investigated the reliability and validity of the ATQ in the Turkish cultural context. It is hoped that with this type of cross-cultural information, the universality of the proposed cognitive constructs can be advocated more reliably. The subjects were 345 university students; the split-half reliability of the ATQ was found to be r = .91 and Cronbach's alpha was .93; and item/total correlations ranged between .36 and .69. The Turkish ATQ correlated well with the BDI (r = .75), and it discriminated successfully between the symptomatic and asymptomatic groups. Factor analysis revealed five factors that were similar to those found in American samples. Nevertheless, some differences were noticed in the relative strength of the factors and in the distribution of items into factor clusters.

Adult↗

How dysfunctional are the dysfunctional attitudes in another culture?

The Dysfunctional Attitude Scale (DAS-A) has been used in many studies to measure depressogenic attitudes, vulnerability to depression and to assess the effectiveness of cognitive therapy. Despite its frequent use in research, no data have yet been reported on its item validity. The purpose of the present study was to investigate the item validity and psychometric properties of the DAS-A in the Turkish cultural context. The subjects were 345 university students. The locally adapted versions of the Beck Depression Inventory and the Automatic Thoughts Questionnaire were also administered. The reliability coefficients and the factor structure of the DAS-A were found to be similar to those reported in the West. However, the total mean was found to be unusually high. The reason for this elevated mean score was found to reside in the response patterns of the subjects to the reverse items. None of these 10 reverse items discriminated the dysphoric and non-dysphoric groups. A closer examination revealed these 10 items to reflect autonomous attitudes. It seems that these 10 reverse items do nothing but distort the mean scores and render cross-cultural comparisons difficult. Recent research on depression shows that, while autonomy may or may not be related to depression, sociotropy has consistent association with it. Researchers in other cultures and those working with minority and immigrant groups are warned against this bias inherent in the DAS-A.

Adult↗

Expression of viral arthritis-tenosynovitis infection in immunosuppressed chickens.

Previously untreated chicks and those treated neonatally with either cyclophosphamide (CY) or infectious bursal disease virus (IBDV) were subcutaneously inoculated with viral arthritis virus ( VAV ) to determine whether suppression of humoral immunity would affect VAV pathogenicity. No difference was apparent in the disease process that occurred in the immunosuppressed versus the nonimmunosuppressed chickens. However, in the immunosuppressed birds, VAV was recovered from the heart and tendon tissues earlier in the postinoculation (PI) period. Also, VAV inoculated immunosuppressed birds carried higher levels of serum gamma globulins at certain PI intervals than the VAV inoculated positive controls or the untreated negative control chickens. It is suggested that the suppression of the bursa of Fabricius (BF) by CY or IBDV did not interfere in the antibody production to VAV , but the antibody produced was qualitatively defective.

Animals↗

Distribution of immunoglobulin-bearing cells in the gut-associated lymphoid tissues of the turkey: effect of antibiotics.

Distribution of immunoglobulin (Ig)-bearing cells in the gut-associated lymphoid tissues of antibiotic treated and untreated control turkeys (Meleagris gallopavo) was compared. Antibiotic treatment was similar to a regimen used in commercial turkey production, which included preincubation dipping of fertile eggs in gentamicin solution, injection of turkeys with gentamicin at hatching, and inclusion of chlortetracycline in the diet. Tissues were examined from turkeys at 3, 7, 14, and 21 days of age with a direct immunofluorescence procedure. Cell distribution in control turkeys was as follows: In the bursa of Fabricius, IgA-carrying cells predominated at 3 days of age, but at later intervals, the 3 classes of Ig-bearing cells were in equal numbers. In the cecal tonsils, IgM- and IgA-bearing cells were in larger numbers at 3 days of age, whereas, the IgG-bearing cells were sparsely distributed. By 7 days of age, IgM cells became more numerous in the cecal tonsils and remained numerous until 21 days of age. At 3 days of age, IgA cells predominated in the small intestines and IgM cells predominated in the large intestine. At 7 and 14 days of age, IgM cells were more numerous in the small and large intestines, but by 21 days of age, IgA cell population equaled that of IgM. The IgG cells were generally sparse in the intestines. Antibiotic treatment often resulted in lower numbers of Ig-positive cells, especially those bearing IgM and IgA. Normal development of the bursa of Fabricius was also retarded in this group.

Animals↗

Distribution of immunoglobulin-bearing cells in the gut-associated lymphoid tissues of the turkey: effect of oral treatment with intestinal microflora.

One-day-old turkeys (Meleagris gallopavo) were orally inoculated with the intestinal contents of an adult turkey, and the intestinal tissues were studied by immunofluorescence for immunoglobulin (Ig)-bearing cells at 3, 7, 14, and 21 days of age. Microflora inoculation increased numbers of Ig-bearing cells in the gut-associated lymphoid tissues; the most uniform effects were observed at 3 days of age. As the birds grew older, this uniformity in response to the microflora inoculation was not evident in all the tissues. In the bursa of Fabricius and the large intestine of the inoculated birds, IgM-bearing cells were more numerous throughout the study period. Compared with noninoculated control turkeys, IgA-bearing cells in the cecal tonsils, and IgG- and IgA-bearing cells in the small intestine were increased at all age intervals.

Aging↗

Maternal antibody and its effect on infectious bursal disease immunization.

Chickens vaccinated with infectious bursal disease virus (IBDV) early in life and revaccinated with an inactivated, oil-adjuvant IBDV vaccine at 18 weeks of age produced and maintained high levels of virus-neutralizing (VN) antibody through 10 months of lay. VN-antibody titers of chicks hatched from eggs laid during the same period closely matched the average VN-antibody titers of the dams. A sequential study of the decline rates of IBDV maternal antibody (MAB) in unvaccinated and IBDV-vaccinated chicks showed that the vaccine virus did not accelerate the antibody depletion rate in vaccinated chicks. Chicks carrying high IBDV MAB showed no active immune response to vaccination with commercial IBDV vaccines. They were also refractory to a pathogenic field isolate of IBDV (FV). However, chicks with low levels of MAB responded to both vaccine virus and the FV, although their response to vaccine virus was milder and delayed.

Animals↗

Leprechaunism in two Turkish patients.

We report two cases of Leprechaunism with the classical features. The first case had hyperglycemia and severe hyperinsulinemia. The postmortem examination of the second child revealed enlargement of both ovaries, islet cell hyperplasia in the pancreas, and cholestasis and paucity of bile ducts in the liver. Cystic changes were noted in the ovaries, and the kidneys contained a few small cortical cysts. Both patients died at early ages.

Abnormalities, Multiple↗