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Biomedical subjects

N Salvatella

Publications and source records attributed to N Salvatella.

10 recordsLinked to original sources
PubMed1989

[Dysplastic nevus syndrome with familial melanoma (type D2)].

A 37 year-old woman presented with type D2 familial dysplastic nevus syndrome with melanoma. A melanoma was excised of her back and more than one hundred pigmented lesions, four of which presented histologic characteristics of dysplastic nevus were observed. Several relatives of her presented multiple nevi and a sister of her mother and a brother of the patient had been diagnosed of melanoma. It is well established that such kind of nevi are precursor for melanomas, particularly familial forms. The clinical identification of such lesions is very simple and facilitates the diagnosis and early treatment of melanoma.

Adult↗
PubMed1988

Porokeratotic eccrine ostial and dermal duct nevus.

We report 2 cases of congenital porokeratotic eccrine nevus in a 5-year-old girl and a 7-year-old boy. The clinical manifestations were those of nevus comedonicus palmaris. The histologic picture consisted of comedo-like dilatations and cornoid lamellae involving the eccrine ostia and ducts. One of the cases showed anomalies in the dermal eccrine ducts. We believe that these lesions are eccrine hamartomas unrelated to porokeratosis. We review similar cases from the literature and discuss the differential diagnosis.

Biopsy↗
PubMed1985

Rhinitis leprosary.

Explore the source record for details and available documents.

Diagnosis, Differential↗
PubMed1984

Actinic granuloma. An ultrastructural study of two cases.

Ultrastructural findings in 2 cases of actinic granuloma are presented. The changes observed at the periphery of the lesion and in the elastic fibers, with early stage of damage, were similar to those described in actinic elastosis. Later, an histiocytic reaction which was apparently directed against damaged elastic fibers was observed. The ultrastructure confirms the light-microscopic findings, but does not clarify the etiology of the lesion or its relation to granuloma annulare.

Aged↗
PubMed1984

Malignant hidroacanthoma simplex. A light microscopic, ultrastructural, and immunohistochemical study of 2 cases.

2 cases of malignant hidroacanthoma simplex are reported. Prominent ultrastructural findings were sparse tonofilaments and villous-like, interdigitating cytoplasmic processes connected by small desmosomes. Positive intracytoplasmic stain for carcinoembryonic antigen was found in 1 case. Benign and malignant eccrine poromas and hidroacanthoma simplex appear to be related neoplasms on the basis of ultrastructural and immunohistochemical findings.

Adenoma, Sweat Gland↗
PubMed1984

[Eosinophilic globules in the Spitz nevus].

We compared the incidence and morphologic appearance of eosinophilic globules in Spitz's nevi, malignant melanoma and compound nevi. Eosinophilic globules were frequently found in Spitz's nevi, specially in those with junctional or compound features. An statistical significant increase of eosinophilic globules was found in Spitz's nevi when compared with malignant melanoma. Eosinophilic globules are not an reliable criteria for a diagnosis of a bening lesion. The use of multiple histologic parameters for differential diagnosis is necessary.

Diagnosis, Differential↗
PubMed1982

[Actinic granuloma. Presentation of 3 cases].

Three cases of actinic granuloma which presented anular lesions with central atrophy in the frontotemporal region are reviewed. Microscopy changes showed the center of the lesion devoid of elastic fibers, an inflammatory reaction at the edge of the lesion and normal elastic fibers in the surrounding area. We discuss the differential diagnosis with granuloma annulare and the possible etiological role of previous actinic damage.

Aged↗