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N Sansoy

Publications and source records attributed to N Sansoy.

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Measurement of cardiac output by the thermodilution method during left thoracotomy in the lateral position in the dog.

The validity of cardiac output measurement by thermodilution in the lateral position during thoracotomy was assessed. Three balloon thermodilution Swan-Ganz catheters were placed in the pulmonary artery trunk and the right and left pulmonary arteries in 12 mongrel dogs, after left thoracotomy had been performed. Cardiac output was measured simultaneously from two of the three sites. The cardiac output measurements show no significant difference related to the location of the catheter extremities: the mean cardiac index was found to be 2.164 +/- 0.448 l/min/m2 from the pulmonary artery trunk, 2.127 +/- 0.404 l/min/m2 from the left branch and 2.116 +/- 0.421 l/min/m2 from the right branch. It is concluded that the measurement of cardiac output during left thoracotomy is valid, whether the thermistor is situated in the pulmonary artery trunk or in a main branch to either the dependent or non-dependent lung.

Animals

[Current data on pain mechanisms (author's transl)].

Nocicepives messages are vehiculated mostly by the A delta and the C fibres, but not exclusively. Spinal cords cells of layers I and V play a very important role in the transmission of painful messages. Spinothalamic pathways include numerous projections among the reticular formation and the mid-brain. This allows the convergence of miscellaneous informations and creates marrow bonds with the structures implicated in comportmental aspects, such as the hypothalamus and the rhinencephalon. Painful message is under the influence of several controls, permanently. There is a metameric control multisegmental; there is a supremetameric one, the raphe nuclei form the essential stake. The discovery of stereospecific sites for the binding of opiates, led to the discovery of the endogenous opiate peptides. These may act as neuromodulators, specifically at the level of the dorsal-horn. Morphine seems to act like them, re-enforcing the physiological mechanism. Biogenic amines such as serotonin are implicated in the regulation of the painful message.

Humans