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Biomedical subjects

N Schulz

Publications and source records attributed to N Schulz.

At least 37 records · Page 2Linked to original sources
PubMed1986

[Genetic studies in etiologically different chronic liver diseases].

In 198 patients with chronic liver diseases of different etiology 16 genetic feature systems were investigated (blood groups, erythrocytic enzymes, immunoglobulin allotypes, proteins). In comparison to a representative normal population significant differences of the frequency of the distribution of phenotypes of various systems were found. In these cases is remarkable that association between genetic markers and hepatopathies were above all proved in their classification according to etiopathogenetic criteria. We evaluate our findings as a reference to the importance of genetic factors in the development of chronic liver diseases.

Blood Group Antigens↗
PubMed1983

Effects of ketotifen on cholinergic induced airway obstruction.

By repeated inhalant carbachol provocation tests on 13 normal and 13 asthmatic subjects, we investigated the effect of ketotifen (as compared with placebo) on the cholinergic responsiveness of the airways. In normal subjects, ketotifen reduced the slope of the linear regression lines, calculated from the airway resistance vs. the intra-pulmonary deposited amount of carbachol (reactivity). By adding a single dose of 80 mg of propranolol the bronchial reactivity was increased. Neither placebo nor ketotifen pretreatment altered the response to propranolol. In asthmatic subjects, the reactivity of the airways to carbachol was reduced after 7 days of ketotifen treatment. Propranolol increased the pre-challenge airway resistance values, and ketotifen did not reduce this bronchoconstrictive action. We could not observe any influence of ketotifen on the potentiation of the carbachol-induced bronchoconstriction. We conclude that ketotifen on the potentiation of the carbachol-induced bronchoconstriction. We conclude that ketotifen reduces the bronchial reactivity as assessed by carbachol inhalation in normal and in asthmatic subjects.

Adolescent↗
PubMed1981

[Qualitative and quantitative behavior of B-lymphocytes and immunoglobulins in the serum of children with acute leukemia after a single immunoglobulin concentrate substitution].

In 19 children affected with acute leukaemia the serum immunoglobulin level was examined. An Ig deficiency treated with a single administration of IgA or IgM concentrate could be detected in 16 of these children. The impact of this single Ig substitution on the serum immunoglobulin level and on B-lymphocytes in the peripheral blood was thrice examined after this substitution. A significant increase of the corresponding Ig class in the serum and a significant decrease of B-lymphocytes in the peripheral blood could be observed.

Adolescent↗
PubMed1979

[Quantitative behavior of B-lymphocytes in infection susceptible children following a single therapeutic substitution with human gamma globulin].

In 15 children with a lowered gammaglobulin level a single substitution with HGG was made, with the impact of this substitution on the number of B-cells in the peripheral blood being examined by means of the direct fluorescence antibody technique. In 9 from 15 children the substitution had no influence on the number of B-cells. However, a significant increase of the number of B-cells could be observed in 6 from 15 children. 14 days after the substitution the number of B-cells lay within the normal range again.

Agammaglobulinemia↗