Biomedical subjects

N Seifert

Publications and source records attributed to N Seifert.

10 recordsLinked to original sources

PubMed2001

Effects of beta-blockers on sexual performance in men with coronary heart disease. A prospective, randomized and double blinded study.

In a prospective trial assessing the effects of beta-blockers on sexual function men with coronary heart disease were randomized to a 4 month treatment with sustained release metoprolol 95 mg or placebo. A standardized and validated self-report questionnaire (KEED = Kölner Erhebungsbogen der Erektilen Dysfunktion) dealing with several aspects of sexual performance in men had to be answered at the beginning and at the end of the study. Based on 65 patients completing the study, sex life seemed unaffected by metoprolol treatment.

Adrenergic beta-Antagonists↗

PubMed2001

Structural brain abnormalities in chronic schizophrenia at the extremes of the outcome spectrum.

OBJECTIVE: This study investigated the relationship between outcome and structural brain abnormalities in schizophrenia. METHOD: Intracranial volume and volumes of the cerebrum, gray and white matter, lateral and third ventricles, frontal lobes, thalamus, and cerebellum were measured in 20 patients with a poor outcome, 25 with a favorable outcome, and 23 healthy comparison subjects with magnetic resonance imaging. RESULTS: Thalamic volume was significantly smaller both in poor-outcome patients and good-outcome patients. In contrast, only poor-outcome patients displayed significantly smaller cerebral gray matter, particularly prefrontal, and enlargement of the lateral and third ventricles. No significant differences were found for intracranial, cerebellar, or cortical CSF volumes. CONCLUSIONS: Smaller thalamic volumes in schizophrenia may reflect a greater susceptibility for the disorder and seem unrelated to outcome. In contrast, gray matter volume loss of the cerebrum, particularly in the frontal lobes, and lateral and third ventricular enlargement appear related to outcome in schizophrenia.

Age of Onset↗

PubMed1996

Supplier involvement through certification: a case study.

The Clarkson Company is located in the Reno-Sparks area of Nevada. We are a manufacturer of slurry valves for mining, pulp and paper, power generation, and various other industries. Because of the diverse nature of the applications for which the valves are used, the product can be configured a vast number of ways. Therefore, we use the assemble-to-order methodology for our master production scheduling. It became apparent over a decade ago that the use of materiel requirements planning (MRP) would aid us in controlling our low volume, high option mix environment. That journey led to The Clarkson Company becoming a Class A user of MRPII in June of 1990.

Certification↗

PubMed1995